Cognitive deficits with chemotherapy in women with breast cancer:: a bibliographic revisión
Background: Patients with breast cancer may experience cognitive difficulties from chemotherapy. This alteration is called Chemoinduced Cognitive Impairment, also known as Chemobrain or Chemofog. Objective: To identify the cognitive profile and the characteristics of the neuropsychological...
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| Formato: | Artículo revista |
| Lenguaje: | Español |
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Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2023
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| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/40533 |
| Aporte de: |
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I10-R327-article-40533 |
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Universidad Nacional de Córdoba |
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R-327 |
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Revista de la Facultad de Ciencias Médicas de Córdoba |
| language |
Español |
| format |
Artículo revista |
| topic |
drug therapy breast neoplasms chemotherapy related cognitive impairment quimioterapia neoplasias de la mama deterioro cognitivo relacionado con la quimioterapia tratamiento farmacológico neoplasias da mama comprometimento cognitivo relacionado á quimioterapia |
| spellingShingle |
drug therapy breast neoplasms chemotherapy related cognitive impairment quimioterapia neoplasias de la mama deterioro cognitivo relacionado con la quimioterapia tratamiento farmacológico neoplasias da mama comprometimento cognitivo relacionado á quimioterapia Arce, Bernardo Grañana, Nora Cognitive deficits with chemotherapy in women with breast cancer:: a bibliographic revisión |
| topic_facet |
drug therapy breast neoplasms chemotherapy related cognitive impairment quimioterapia neoplasias de la mama deterioro cognitivo relacionado con la quimioterapia tratamiento farmacológico neoplasias da mama comprometimento cognitivo relacionado á quimioterapia |
| author |
Arce, Bernardo Grañana, Nora |
| author_facet |
Arce, Bernardo Grañana, Nora |
| author_sort |
Arce, Bernardo |
| title |
Cognitive deficits with chemotherapy in women with breast cancer:: a bibliographic revisión |
| title_short |
Cognitive deficits with chemotherapy in women with breast cancer:: a bibliographic revisión |
| title_full |
Cognitive deficits with chemotherapy in women with breast cancer:: a bibliographic revisión |
| title_fullStr |
Cognitive deficits with chemotherapy in women with breast cancer:: a bibliographic revisión |
| title_full_unstemmed |
Cognitive deficits with chemotherapy in women with breast cancer:: a bibliographic revisión |
| title_sort |
cognitive deficits with chemotherapy in women with breast cancer:: a bibliographic revisión |
| description |
Background: Patients with breast cancer may experience cognitive difficulties from chemotherapy. This alteration is called Chemoinduced Cognitive Impairment, also known as Chemobrain or Chemofog. Objective: To identify the cognitive profile and the characteristics of the neuropsychological assessment in this population. Method: PubMed, SpringerLink and SciELO databases were revised. Articles from 1994 to September 2021 were selected. Keywords related to the study topic were used. Results: Chemotherapy can cause cognitive impairment between 15 and 50% of women. This disturbance may be from multiple aetiologies and can be associated with biological factors and functional and/or structural changes of the CNS. Sociodemographic, clinical and psychological factors should be considered as modulating variables. It manifests mainly with memory problems, executive function, attention and processing speed impairment. It can be measured through neuropsychological evaluation instruments. Discussion and conclusion: We suggest that chemo-induced cognitive impairment should be included to the informed consent. Further development of longitudinal studies complemented with neuroimages that allow us to advance in the knowledge of this problem is recommended. A neuropsychological protocol is proposed, which includes screening tests, clinical scales, specific cognitive tests and quality of life questionnaires, within the recommendations of the International Cognition and Cancer Task Force |
| publisher |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2023 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/40533 |
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I10-R327-article-405332023-08-11T16:02:34Z Cognitive deficits with chemotherapy in women with breast cancer:: a bibliographic revisión Alteraciones cognitivas por quimioterapia en pacientes con cáncer de mama:: una revisión bibliográfica Alterações cognitivas decorrentes da quimioterapia em pacientes com câncer de mama: : uma revisão de literatura Arce, Bernardo Grañana, Nora drug therapy breast neoplasms chemotherapy related cognitive impairment quimioterapia neoplasias de la mama deterioro cognitivo relacionado con la quimioterapia tratamiento farmacológico neoplasias da mama comprometimento cognitivo relacionado á quimioterapia Background: Patients with breast cancer may experience cognitive difficulties from chemotherapy. This alteration is called Chemoinduced Cognitive Impairment, also known as Chemobrain or Chemofog. Objective: To identify the cognitive profile and the characteristics of the neuropsychological assessment in this population. Method: PubMed, SpringerLink and SciELO databases were revised. Articles from 1994 to September 2021 were selected. Keywords related to the study topic were used. Results: Chemotherapy can cause cognitive impairment between 15 and 50% of women. This disturbance may be from multiple aetiologies and can be associated with biological factors and functional and/or structural changes of the CNS. Sociodemographic, clinical and psychological factors should be considered as modulating variables. It manifests mainly with memory problems, executive function, attention and processing speed impairment. It can be measured through neuropsychological evaluation instruments. Discussion and conclusion: We suggest that chemo-induced cognitive impairment should be included to the informed consent. Further development of longitudinal studies complemented with neuroimages that allow us to advance in the knowledge of this problem is recommended. A neuropsychological protocol is proposed, which includes screening tests, clinical scales, specific cognitive tests and quality of life questionnaires, within the recommendations of the International Cognition and Cancer Task Force Antecedentes: Los pacientes con cáncer de mama pueden experimentar dificultades cognitivas por recibir quimioterapia. Dicha alteración es denominada Deterioro Cognitivo Quimioinducido, también es conocida como Chemobrain o Chemofog. Objetivo: Identificar el perfil cognitivo y las características de la evaluación neuropsicológica de esta población. Método: Se consultaron las bases de datos PubMed, SpringerLink y SciELO. Se seleccionaron artículos de 1994 hasta septiembre de 2021. Fueron utilizadas palabras claves relacionadas con el tema de estudio. Resultados: La quimioterapia puede producir un deterioro cognitivo entre el 15 y el 50% de las mujeres. Dicha alteración es de etiología múltiple y puede asociarse a factores biológicos y a cambios funcionales y/o estructurales del SNC. Se deben de considerar los factores sociodemográficos, clínicos y psicológicos como variables moduladoras. Se manifiesta principalmente en problemas de memoria, función ejecutiva, atención y velocidad de procesamiento. Esta alteración puede ser mensurada a través de los instrumentos de evaluación neuropsicológica disponibles. Discusión y conclusión: Se sugiere que la afectación cognitiva quimioinducida sea incorporada en el consentimiento informado. Se recomienda un mayor desarrollo de estudios longitudinales que se complementen con técnicas de neuroimágenes que permitan avanzar en el conocimiento de esta problemática. Se propone un protocolo de evaluación neuropsicológica, que incluye pruebas de screening, escalas clínicas, test neuropsicológicos específicos y de calidad de vida, según las recomendaciones del International Cognition and Cancer Task Force. Introdução: Pacientes com câncer de mama podem apresentar dificuldades cognitivas ao receber quimioterapia. Esta alteração é chamada de Comprometimento Cognitivo Quimioinduzido, também é conhecido como Chemobrain ou Chemofog. Objetivo: Identificar o perfil cognitivo e as características da avaliação neuropsicológica dessa população. Método: Foram consultadas as bases de dados PubMed, SpringerLink e SciELO. Foram selecionados artigos de 1994 a setembro de 2021. Foram utilizadas palavras-chave relacionadas ao tema do estudo. Resultados: A quimioterapia pode causar comprometimento cognitivo entre 15 e 50% das mulheres. Essa alteração é de etiologia múltipla e pode estar associada a fatores biológicos e alterações funcionais e/ou estruturais do SNC. Fatores sociodemográficos, clínicos e psicológicos devem ser considerados como variáveis moduladoras. Manifesta-se principalmente em problemas de memória, função executiva, atenção e velocidade de processamento. Essa alteração pode ser mensurada por meio dos instrumentos de avaliação neuropsicológica disponíveis. Discussão e conclusão: Sugere-se que o comprometimento cognitivo induzido pela quimioterapia seja incorporado ao consentimento informado. Recomenda-se um maior desenvolvimento de estudos longitudinais que sejam complementados com técnicas de neuroimagem que nos permitam avançar no conhecimento deste problema. Propõe-se um protocolo de avaliação neuropsicológica, que inclui testes de triagem, escalas clínicas, testes neuropsicológicos específicos e de qualidade de vida, de acordo com as recomendações da International Cognition and Cancer Task Force.. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2023-06-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion text texto texto application/pdf text/html https://revistas.unc.edu.ar/index.php/med/article/view/40533 10.31053/1853.0605.v80.n2.40533 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 80 No. 2 (2023); 126-133 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 80 Núm. 2 (2023); 126-133 Revista da Faculdade de Ciências Médicas de Córdoba; v. 80 n. 2 (2023); 126-133 1853-0605 0014-6722 10.31053/1853.0605.v80.n2 spa https://revistas.unc.edu.ar/index.php/med/article/view/40533/41787 https://revistas.unc.edu.ar/index.php/med/article/view/40533/41799 Derechos de autor 2023 Universidad Nacional de Córdoba http://creativecommons.org/licenses/by-nc/4.0 |