Transdisciplinarity in the approach to amyloidosis
The increasing complexity in the approach to diseases challenges the development of a new paradigm of care that crosses disciplinary limits, where professionals from different disciplines approach a problem applying their expertise, respecting the knowledge of the other and contributing to the globa...
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| Formato: | Artículo revista |
| Lenguaje: | Español |
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Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2021
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| Materias: | |
| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/32341 |
| Aporte de: |
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I10-R327-article-32341 |
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ojs |
| institution |
Universidad Nacional de Córdoba |
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I-10 |
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R-327 |
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Revista de la Facultad de Ciencias Médicas de Córdoba |
| language |
Español |
| format |
Artículo revista |
| topic |
amyloidosys salivary glands biopsy biopsia amiloidosis glandulas salivales amiloidose glândulas salivares biopsia |
| spellingShingle |
amyloidosys salivary glands biopsy biopsia amiloidosis glandulas salivales amiloidose glândulas salivares biopsia Alfonsín, Amalia Ernestina Escada, Sofia Stephanie Kohan, Dana Valeo Chulvi, Melina Paula Posadas Martínez, María Lourdes Aguirre, María Adela Nucifora, Elsa Mercedes Transdisciplinarity in the approach to amyloidosis |
| topic_facet |
amyloidosys salivary glands biopsy biopsia amiloidosis glandulas salivales amiloidose glândulas salivares biopsia |
| author |
Alfonsín, Amalia Ernestina Escada, Sofia Stephanie Kohan, Dana Valeo Chulvi, Melina Paula Posadas Martínez, María Lourdes Aguirre, María Adela Nucifora, Elsa Mercedes |
| author_facet |
Alfonsín, Amalia Ernestina Escada, Sofia Stephanie Kohan, Dana Valeo Chulvi, Melina Paula Posadas Martínez, María Lourdes Aguirre, María Adela Nucifora, Elsa Mercedes |
| author_sort |
Alfonsín, Amalia Ernestina |
| title |
Transdisciplinarity in the approach to amyloidosis |
| title_short |
Transdisciplinarity in the approach to amyloidosis |
| title_full |
Transdisciplinarity in the approach to amyloidosis |
| title_fullStr |
Transdisciplinarity in the approach to amyloidosis |
| title_full_unstemmed |
Transdisciplinarity in the approach to amyloidosis |
| title_sort |
transdisciplinarity in the approach to amyloidosis |
| description |
The increasing complexity in the approach to diseases challenges the development of a new paradigm of care that crosses disciplinary limits, where professionals from different disciplines approach a problem applying their expertise, respecting the knowledge of the other and contributing to the global view of the problem. Amyloidoses are rare diseases. The diagnosis is based on the biopsy of those organs in which amyloid infiltration is suspected. There is an increased risk of bleeding associated with these procedures. Therefore, the availability of obtaining samples from certain sites with less invasive accesses, such as the minor salivary glands (GSM), represent an alternative. Objectives: Describe the experiences of GSM biopsies as a diagnostic tool in the detection of amyloidosis and its intra and postoperative complications. - Estimate the diagnostic performance. The design is a cross-sectional cohort. All patients with a suspected diagnosis of amyloidosis were consecutively included, between August 2018-September 2020. Results: 23 biopsies were performed with minimally invasive procedures. 60.86% were male and the average age was 66 years. The prevalence of amyloidosis was 33%. The sensitivity was 55% and the specificity 100%. One patient had more bleeding than usual during the procedure and none had postoperative complications. Conclusions: GSM biopsy experiences were described as a diagnostic tool for amyloidosis, reporting a slight intraoperative complication and no postoperative complication. The test achieved a sensitivity of 55% and a specificity of 100%. |
| publisher |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2021 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/32341 |
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I10-R327-article-323412021-11-18T12:43:09Z Transdisciplinarity in the approach to amyloidosis La transdisciplinariedad en el abordaje de la amiloidosis Transdisciplinaridade na abordagem da amiloidose Alfonsín, Amalia Ernestina Escada, Sofia Stephanie Kohan, Dana Valeo Chulvi, Melina Paula Posadas Martínez, María Lourdes Aguirre, María Adela Nucifora, Elsa Mercedes amyloidosys salivary glands biopsy biopsia amiloidosis glandulas salivales amiloidose glândulas salivares biopsia The increasing complexity in the approach to diseases challenges the development of a new paradigm of care that crosses disciplinary limits, where professionals from different disciplines approach a problem applying their expertise, respecting the knowledge of the other and contributing to the global view of the problem. Amyloidoses are rare diseases. The diagnosis is based on the biopsy of those organs in which amyloid infiltration is suspected. There is an increased risk of bleeding associated with these procedures. Therefore, the availability of obtaining samples from certain sites with less invasive accesses, such as the minor salivary glands (GSM), represent an alternative. Objectives: Describe the experiences of GSM biopsies as a diagnostic tool in the detection of amyloidosis and its intra and postoperative complications. - Estimate the diagnostic performance. The design is a cross-sectional cohort. All patients with a suspected diagnosis of amyloidosis were consecutively included, between August 2018-September 2020. Results: 23 biopsies were performed with minimally invasive procedures. 60.86% were male and the average age was 66 years. The prevalence of amyloidosis was 33%. The sensitivity was 55% and the specificity 100%. One patient had more bleeding than usual during the procedure and none had postoperative complications. Conclusions: GSM biopsy experiences were described as a diagnostic tool for amyloidosis, reporting a slight intraoperative complication and no postoperative complication. The test achieved a sensitivity of 55% and a specificity of 100%. La creciente complejidad en el abordaje de las enfermedades desafía a desarrollar un nuevo paradigma de atención que atraviese los límites disciplinarios, donde profesionales de diferentes especialidades abordan un problema aplicando su expertise, respetando el conocimiento del otro y contribuyendo a la mirada global de la problemática. Las amiloidosis son enfermedades raras. El diagnóstico se basa en la biopsia de aquellos órganos en los que se sospecha de infiltración amiloidea. Existe un aumento del riesgo de sangrado asociado con estos procedimientos. Por ello, la disponibilidad de obtener muestras de determinados sitios con accesos menos invasivos, como las glándulas salivales menores (GSM), representan una alternativa. Objetivos: Describir las experiencias de biopsias GSM como herramienta diagnóstica en la detección de amiloidosis y sus complicaciones intra y postoperatorias. Estimar la performance diagnóstica. El diseño es de cohorte transversal. Se incluyeron consecutivamente todos los pacientes con sospecha de diagnóstico de amiloidosis, entre agosto 2018-septiembre 2020. Resultados: Se efectuaron 23 biopsias con procedimientos mínimamente invasivos. El 60,86 % fueron de sexo masculino y la media de edad 66 años. La prevalencia de amiloidosis fue del 33%. La sensibilidad fue del 55% y la especificidad del 100 %. Un paciente presentó mayor sangrado que lo habitual durante el procedimiento y ninguno presentó complicaciones postoperatorias. Conclusiones: Se describieron las experiencias de biopsia de GSM como herramienta diagnóstica de amiloidosis, reportando una leve complicación intraoperatoria y nula posoperatoria. La prueba alcanzó una sensibilidad del 55 % y una especificidad del 100 %. A crescente complexidade na abordagem das doenças desafia o desenvolvimento de um novo paradigma de cuidado que extrapola os limites disciplinares, onde profissionais de diferentes disciplinas abordam um problema aplicando suas competências, respeitando o conhecimento do outro e contribuindo para a visão global do problema. As amiloidoses são doenças raras. O diagnóstico é baseado na biópsia dos órgãos em que há suspeita de infiltração amilóide. Há um risco aumentado de sangramento associado a esses procedimentos. Portanto, a disponibilidade de obtenção de amostras em determinados locais com acessos menos invasivos, como as glândulas salivares menores (GSM), representa uma alternativa. Metas: Descrever as experiências das biópsias GSM como ferramenta diagnóstica na detecção da amiloidose e suas complicações intra e pós-operatórias. - Estimar o desempenho diagnóstico. O desenho é uma coorte transversal. Todos os pacientes com suspeita de diagnóstico de amiloidose foram incluídos consecutivamente, entre agosto de 2018 e setembro de 2020. Resultados: 23 biópsias foram realizadas com procedimentos minimamente invasivos. 60,86% eram do sexo masculino e a idade média era de 66 anos. A prevalência de amiloidose foi de 33%. A sensibilidade foi de 55% e a especificidade de 100%. Um paciente teve mais sangramento que o normal durante o procedimento e nenhum apresentou complicações pós-operatórias. Conclusões: Foram descritas experiências de biópsia GSM como ferramenta diagnóstica para amiloidose, relatando uma leve complicação intra-operatória e nenhuma complicação pós-operatória. O teste atingiu uma sensibilidade de 55% e uma especificidade de 100%. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2021-09-18 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf text/html https://revistas.unc.edu.ar/index.php/med/article/view/32341 10.31053/1853.0605.v78.n3.32341 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 78 No. 3 (2021); 313-316 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 78 Núm. 3 (2021); 313-316 Revista da Faculdade de Ciências Médicas de Córdoba; v. 78 n. 3 (2021); 313-316 1853-0605 0014-6722 10.31053/1853.0605.v78.n3 spa https://revistas.unc.edu.ar/index.php/med/article/view/32341/35224 https://revistas.unc.edu.ar/index.php/med/article/view/32341/35293 Derechos de autor 2021 Universidad Nacional de Córdoba http://creativecommons.org/licenses/by-nc/4.0 |