Histochemical modifications of sugar residues in glycoconjugates of human palatine glands during development and maduration.
Antecedents,- Most of the literature has focused on the morphological and histochemica] characteristics of palatine glancis during the development histogenesis and maturation process. However, there are no publications regarding protein glycosylation and the distribution of glycoproteins with N and...
Guardado en:
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Artículo revista |
| Lenguaje: | Español |
| Publicado: |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2019
|
| Materias: | |
| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/26721 |
| Aporte de: |
| id |
I10-R327-article-26721 |
|---|---|
| record_format |
ojs |
| institution |
Universidad Nacional de Córdoba |
| institution_str |
I-10 |
| repository_str |
R-327 |
| container_title_str |
Revista de la Facultad de Ciencias Médicas de Córdoba |
| language |
Español |
| format |
Artículo revista |
| topic |
palatine glands development maturation sugars histochemistry glándulas palatinas desarrollo maduración azúcares histoquímica |
| spellingShingle |
palatine glands development maturation sugars histochemistry glándulas palatinas desarrollo maduración azúcares histoquímica Samar, María E Ávila, Rodolfo E Fernández, Javier Fernández, René Rugani, Nelson R Massone, Adriana Olmedo, Luis Histochemical modifications of sugar residues in glycoconjugates of human palatine glands during development and maduration. |
| topic_facet |
palatine glands development maturation sugars histochemistry glándulas palatinas desarrollo maduración azúcares histoquímica |
| author |
Samar, María E Ávila, Rodolfo E Fernández, Javier Fernández, René Rugani, Nelson R Massone, Adriana Olmedo, Luis |
| author_facet |
Samar, María E Ávila, Rodolfo E Fernández, Javier Fernández, René Rugani, Nelson R Massone, Adriana Olmedo, Luis |
| author_sort |
Samar, María E |
| title |
Histochemical modifications of sugar residues in glycoconjugates of human palatine glands during development and maduration. |
| title_short |
Histochemical modifications of sugar residues in glycoconjugates of human palatine glands during development and maduration. |
| title_full |
Histochemical modifications of sugar residues in glycoconjugates of human palatine glands during development and maduration. |
| title_fullStr |
Histochemical modifications of sugar residues in glycoconjugates of human palatine glands during development and maduration. |
| title_full_unstemmed |
Histochemical modifications of sugar residues in glycoconjugates of human palatine glands during development and maduration. |
| title_sort |
histochemical modifications of sugar residues in glycoconjugates of human palatine glands during development and maduration. |
| description |
Antecedents,- Most of the literature has focused on the morphological and histochemica] characteristics of palatine glancis during the development histogenesis and maturation process. However, there are no publications regarding protein glycosylation and the distribution of glycoproteins with N and 0-glycoside bonds, and their possihle functional role. Objective .- Based on this background we committed ourselves to studying the human palatine glands in clifferent age groups in order to determine the beginining of mucine secretion and the presence of glycoproteins with N and 0-glycoside borids during the processes of differentiation and maturation. Materials and method. - Human palatine glands were obtaincd from embryos, fetuses, newborn infants, youngsters and aclults. They were studied using histochemical methods (PAS, Dane, Alcian blue, Toluidine blue), and lectin histochemistry. Results.- The variations observed ¡o glycoconjugates during the development and maturation of human palaline glands show that secretion starts at early stagcs of prenatal development it is macle up of various sugars that might play an important role jo the pre-natal and postnatal l)eriocls. Conclusions.- The study of modifications ¡u sugar rcsiducs in the human l)alatine glands during embryogenesis, differcntiation and maturation processes aliows us to have further knowledge of their liistophysioloy and possible changes taking place during aging. This study may also help to understand pathologieal processes ¡o mature salival-y glands. |
| publisher |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2019 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/26721 |
| work_keys_str_mv |
AT samarmariae histochemicalmodificationsofsugarresiduesinglycoconjugatesofhumanpalatineglandsduringdevelopmentandmaduration AT avilarodolfoe histochemicalmodificationsofsugarresiduesinglycoconjugatesofhumanpalatineglandsduringdevelopmentandmaduration AT fernandezjavier histochemicalmodificationsofsugarresiduesinglycoconjugatesofhumanpalatineglandsduringdevelopmentandmaduration AT fernandezrene histochemicalmodificationsofsugarresiduesinglycoconjugatesofhumanpalatineglandsduringdevelopmentandmaduration AT ruganinelsonr histochemicalmodificationsofsugarresiduesinglycoconjugatesofhumanpalatineglandsduringdevelopmentandmaduration AT massoneadriana histochemicalmodificationsofsugarresiduesinglycoconjugatesofhumanpalatineglandsduringdevelopmentandmaduration AT olmedoluis histochemicalmodificationsofsugarresiduesinglycoconjugatesofhumanpalatineglandsduringdevelopmentandmaduration AT samarmariae modificacioneshistoquimicasdelosresiduosazucaresenlosglucoconjugadosdelasglandulaspalatinashumanasdurantesuderrolloymaduracion AT avilarodolfoe modificacioneshistoquimicasdelosresiduosazucaresenlosglucoconjugadosdelasglandulaspalatinashumanasdurantesuderrolloymaduracion AT fernandezjavier modificacioneshistoquimicasdelosresiduosazucaresenlosglucoconjugadosdelasglandulaspalatinashumanasdurantesuderrolloymaduracion AT fernandezrene modificacioneshistoquimicasdelosresiduosazucaresenlosglucoconjugadosdelasglandulaspalatinashumanasdurantesuderrolloymaduracion AT ruganinelsonr modificacioneshistoquimicasdelosresiduosazucaresenlosglucoconjugadosdelasglandulaspalatinashumanasdurantesuderrolloymaduracion AT massoneadriana modificacioneshistoquimicasdelosresiduosazucaresenlosglucoconjugadosdelasglandulaspalatinashumanasdurantesuderrolloymaduracion AT olmedoluis modificacioneshistoquimicasdelosresiduosazucaresenlosglucoconjugadosdelasglandulaspalatinashumanasdurantesuderrolloymaduracion |
| first_indexed |
2024-09-03T21:01:34Z |
| last_indexed |
2024-09-03T21:01:34Z |
| _version_ |
1809210193638064128 |
| spelling |
I10-R327-article-267212024-08-27T18:27:09Z Histochemical modifications of sugar residues in glycoconjugates of human palatine glands during development and maduration. Modificaciones histoquímicas de los residuos azucares en los glucoconjugados de las glándulas palatinas humanas durante su derrollo y maduración Samar, María E Ávila, Rodolfo E Fernández, Javier Fernández, René Rugani, Nelson R Massone, Adriana Olmedo, Luis palatine glands development maturation sugars histochemistry glándulas palatinas desarrollo maduración azúcares histoquímica Antecedents,- Most of the literature has focused on the morphological and histochemica] characteristics of palatine glancis during the development histogenesis and maturation process. However, there are no publications regarding protein glycosylation and the distribution of glycoproteins with N and 0-glycoside bonds, and their possihle functional role. Objective .- Based on this background we committed ourselves to studying the human palatine glands in clifferent age groups in order to determine the beginining of mucine secretion and the presence of glycoproteins with N and 0-glycoside borids during the processes of differentiation and maturation. Materials and method. - Human palatine glands were obtaincd from embryos, fetuses, newborn infants, youngsters and aclults. They were studied using histochemical methods (PAS, Dane, Alcian blue, Toluidine blue), and lectin histochemistry. Results.- The variations observed ¡o glycoconjugates during the development and maturation of human palaline glands show that secretion starts at early stagcs of prenatal development it is macle up of various sugars that might play an important role jo the pre-natal and postnatal l)eriocls. Conclusions.- The study of modifications ¡u sugar rcsiducs in the human l)alatine glands during embryogenesis, differcntiation and maturation processes aliows us to have further knowledge of their liistophysioloy and possible changes taking place during aging. This study may also help to understand pathologieal processes ¡o mature salival-y glands. Antecedentes: Algunos investigadores estudiaron las características morfológicas e histoquímicas durante el desarrollo, histogénesis y maduración de las glándulas palatinas, en tanto que no se conocen observaciones sobre el patrón de glicosilación de sus proteínas y la distribución de glicoproteínas con uniones N y 0-glucosídicas y sus posibles implicancias funcionales. Objetivos: En base a estos antecedentes nos propusimos investigar con histoquímica básica y lectinhistoquímica las glándulas palatinas humanas de diferentes grupos etanos para determinar el inicio de la secreción de mucinas y la presencia de glicoproteínas con uniones Ny 0-glucosídicas durante la diferenciación y maduración glandular. Materiales y métodos: Glándulas palatinas humanas de embriones y fetos, recién nacidos, jóvenes y adultos fueron estudiadas con métodos histoquímicos (PAS, Dane, Alejan blue a pl-I 2,5 y 1,0. Azul de toluidina) y lectinhistoquímica. Resultados: Las variaciones observadas en los glicoconjugados durante el desarrollo y maduración de las glándulas palatinas humanas demuestran que su secreción comienza en etapas tempranas del desarrollo prenatal y está compuesta por una variedad de azúcares que cumplirían un papel fundamental en los periodos prenatales y postnatales. Conclusiones: El estudio de las modificaciones de los residuos azúcares en las glándulas palatinas humanas durante la embriogénesis, diferenciación y maduración, nos permite obtener una mayor información sobre su histofisiología y sobre los potenciales cambios durante el envejecimiento y procesos patológicos de las glándulas salivales maduras. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2019-12-03 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/26721 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 63 No. 2 (2006); 13 -19 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 63 Núm. 2 (2006); 13 -19 Revista da Faculdade de Ciências Médicas de Córdoba; v. 63 n. 2 (2006); 13 -19 1853-0605 0014-6722 spa https://revistas.unc.edu.ar/index.php/med/article/view/26721/28394 Derechos de autor 2019 Universidad Nacional de Córdoba https://creativecommons.org/licenses/by-nc/4.0 |