Essential mixed cryoglobulinemia type II: case report

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The cryoglobulinemic syndrome is produced by precipitating immunoglobulins at low temperatures. Its production is associated with several causes, such as lymphoproliferative disorders, chronic infections and autoimmune disorders. However, the etiology is unknow. There are three types of cryoglobulin...

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Autores principales: Mazzota, Marcos, Dotto, Beatriz, Salazar, Viviana, Herrero, Mónica, Sesín, Ana María, Dionisio de Cabalier, María Elisa, Mukdsi, Jorge
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2018
Materias:
crioglobulinemia esencial
vasculitis leucocitoclástica
glomerulonefritis
mixed cryoglobulinemia
cryoglobulinaemic vasculitis
glomerulonephritis
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/17550
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Revista de la Facultad de Ciencias Médicas de Córdoba de Universidad Nacional de Córdoba
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spelling I10-R327-article-175502024-08-27T18:20:45Z Essential mixed cryoglobulinemia type II: case report Crioglobulinemia mixta esencial tipo II: presentación de un caso Mazzota, Marcos Dotto, Beatriz Salazar, Viviana Herrero, Mónica Sesín, Ana María Dionisio de Cabalier, María Elisa Mukdsi, Jorge crioglobulinemia esencial vasculitis leucocitoclástica glomerulonefritis mixed cryoglobulinemia cryoglobulinaemic vasculitis glomerulonephritis The cryoglobulinemic syndrome is produced by precipitating immunoglobulins at low temperatures. Its production is associated with several causes, such as lymphoproliferative disorders, chronic infections and autoimmune disorders. However, the etiology is unknow. There are three types of cryoglobulins. Type II and III are the mixed. Type III produce a systemic vasculitis with diverse clinical manifestations. Palpable purpura is the most common, accompanied by arthralgia, neuropathy and type I membranoproliferative glomerulonephritis. We present a case of a 71 years old male patient with renal failure, nephritic syndrome, arterial hypertension and palpable purpuric skin lesions in members, thorax and abdomen. During hospitalization essential mixed cryoglobulinemia associated with cutaneous leukocytoclastic vasculitis and type I membranoproliferative glomerulonephritis was  diagnosed. Complementary methods, treatment instituted and the patient's clinical course are described. El síndrome crioglobulinémico es producido por inmunoglobulinas que precipitan reversiblemente a bajas temperaturas, llamadas crioglobulinas. Su producción se asocia a varias causas, como desórdenes linfoproliferativos, infecciones crónicas y trastornos autoinmunitarios. No obstante, en muchos casos la etiología no logra determinarse. Existen tres tipos, siendo las de tipo II y III las que forman parte de las denominadas crioglobulinemias mixtas. Estas últimas producen un cuadro de vasculitis sistémica con manifestaciones clínicas diversas. La púrpura palpable es la más frecuente, acompañada en forma variable por artralgias, neuropatía y afección renal en forma de glomerulonefritis membranoproliferativa de tipo I. Presentamos el caso clínico de un paciente de sexo masculino de 71 años de edad con insuficiencia renal, síndrome nefrítico, hipertensión arterial y lesiones cutáneas purpúricas palpables ambos miembros, tórax y abdomen. Durante la internación se diagnostica crioglobulinemia mixta esencial asociada a vasculitis leucocitoclástica cutánea y glomerulonefritis membranoproliferativa tipo I. Describimos los métodos complementarios utilizados para llegar al diagnóstico, el tratamiento instituido y la evolución clínica del paciente.  Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2018-12-02 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion text/html application/pdf image/gif image/gif https://revistas.unc.edu.ar/index.php/med/article/view/17550 10.31053/1853.0605.v74.n3.17550 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 75 No. 4 (2018); 292-298 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 75 Núm. 4 (2018); 292-298 Revista da Faculdade de Ciências Médicas de Córdoba; v. 75 n. 4 (2018); 292-298 1853-0605 0014-6722 10.31053/1853.0605.v75.n4 spa https://revistas.unc.edu.ar/index.php/med/article/view/17550/22190 https://revistas.unc.edu.ar/index.php/med/article/view/17550/22539 https://revistas.unc.edu.ar/index.php/med/article/view/17550/26588 https://revistas.unc.edu.ar/index.php/med/article/view/17550/26589 Derechos de autor 2018 Universidad Nacional de Córdoba https://creativecommons.org/licenses/by-nc/4.0
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-327
container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
language Español
format Artículo revista
topic crioglobulinemia esencial
vasculitis leucocitoclástica
glomerulonefritis
mixed cryoglobulinemia
cryoglobulinaemic vasculitis
glomerulonephritis
spellingShingle crioglobulinemia esencial
vasculitis leucocitoclástica
glomerulonefritis
mixed cryoglobulinemia
cryoglobulinaemic vasculitis
glomerulonephritis
Mazzota, Marcos
Dotto, Beatriz
Salazar, Viviana
Herrero, Mónica
Sesín, Ana María
Dionisio de Cabalier, María Elisa
Mukdsi, Jorge
Essential mixed cryoglobulinemia type II: case report
topic_facet crioglobulinemia esencial
vasculitis leucocitoclástica
glomerulonefritis
mixed cryoglobulinemia
cryoglobulinaemic vasculitis
glomerulonephritis
author Mazzota, Marcos
Dotto, Beatriz
Salazar, Viviana
Herrero, Mónica
Sesín, Ana María
Dionisio de Cabalier, María Elisa
Mukdsi, Jorge
author_facet Mazzota, Marcos
Dotto, Beatriz
Salazar, Viviana
Herrero, Mónica
Sesín, Ana María
Dionisio de Cabalier, María Elisa
Mukdsi, Jorge
author_sort Mazzota, Marcos
title Essential mixed cryoglobulinemia type II: case report
title_short Essential mixed cryoglobulinemia type II: case report
title_full Essential mixed cryoglobulinemia type II: case report
title_fullStr Essential mixed cryoglobulinemia type II: case report
title_full_unstemmed Essential mixed cryoglobulinemia type II: case report
title_sort essential mixed cryoglobulinemia type ii: case report
description The cryoglobulinemic syndrome is produced by precipitating immunoglobulins at low temperatures. Its production is associated with several causes, such as lymphoproliferative disorders, chronic infections and autoimmune disorders. However, the etiology is unknow. There are three types of cryoglobulins. Type II and III are the mixed. Type III produce a systemic vasculitis with diverse clinical manifestations. Palpable purpura is the most common, accompanied by arthralgia, neuropathy and type I membranoproliferative glomerulonephritis. We present a case of a 71 years old male patient with renal failure, nephritic syndrome, arterial hypertension and palpable purpuric skin lesions in members, thorax and abdomen. During hospitalization essential mixed cryoglobulinemia associated with cutaneous leukocytoclastic vasculitis and type I membranoproliferative glomerulonephritis was  diagnosed. Complementary methods, treatment instituted and the patient's clinical course are described.
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2018
url https://revistas.unc.edu.ar/index.php/med/article/view/17550
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first_indexed 2024-09-03T20:58:36Z
last_indexed 2024-09-03T20:58:36Z
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