A multiscale model of virus pandemic: Heterogeneous interactive entities in a globally connected world

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This paper is devoted to the multidisciplinary modelling of a pandemic initiated by an aggressive virus, specifically the so-called SARS–CoV–2 Severe Acute Respiratory Syndrome, corona virus n.2. The study is developed within a multiscale framework accounting for the interaction of different spatial...

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Autores principales:	Bellomo, Nicola, Bingham, Richard, Chaplain, Mark A. J., Dosi, Giovanni, Forni, Guido, Knopoff, Damian A., Lowengrub, John, Twarock, Reidun, Virgillito, Maria Enrica
Formato:	article
Lenguaje:	Inglés
Publicado:	World Scientific 2020
Materias:	Covid 19 living systems immune competition complexity multiscale problems spatial patterns networks intracellular infection dynamics SARS-CoV-2
Acceso en línea:	https://doi.org/10.1142/S0218202520500323 http://hdl.handle.net/11086/16280
Aporte de:	Repositorio Digital Universitario (UNC) de Universidad Nacional de Córdoba

id	I10-R14111086-16280
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institution	Universidad Nacional de Córdoba
institution_str	I-10
repository_str	R-141
collection	Repositorio Digital Universitario (UNC)
language	Inglés
topic	Covid 19 living systems immune competition complexity multiscale problems spatial patterns networks intracellular infection dynamics SARS-CoV-2
spellingShingle	Covid 19 living systems immune competition complexity multiscale problems spatial patterns networks intracellular infection dynamics SARS-CoV-2 Bellomo, Nicola Bingham, Richard Chaplain, Mark A. J. Dosi, Giovanni Forni, Guido Knopoff, Damian A. Lowengrub, John Twarock, Reidun Virgillito, Maria Enrica A multiscale model of virus pandemic: Heterogeneous interactive entities in a globally connected world
topic_facet	Covid 19 living systems immune competition complexity multiscale problems spatial patterns networks intracellular infection dynamics SARS-CoV-2
description	This paper is devoted to the multidisciplinary modelling of a pandemic initiated by an aggressive virus, specifically the so-called SARS–CoV–2 Severe Acute Respiratory Syndrome, corona virus n.2. The study is developed within a multiscale framework accounting for the interaction of different spatial scales, from the small scale of the virus itself and cells, to the large scale of individuals and further up to the collective behaviour of populations. An interdisciplinary vision is developed thanks to the contributions of epidemiologists, immunologists and economists as well as those of mathematical modellers. The first part of the contents is devoted to understanding the complex features of the system and to the design of a modelling rationale. The modelling approach is treated in the second part of the paper by showing both how the virus propagates into infected individuals, successfully and not successfully recovered, and also the spatial patterns, which are subsequently studied by kinetic and lattice models. The third part reports the contribution of research in the fields of virology, epidemiology, immune competition, and economy focussed also on social behaviours. Finally, a critical analysis is proposed looking ahead to research perspectives.
format	article
author	Bellomo, Nicola Bingham, Richard Chaplain, Mark A. J. Dosi, Giovanni Forni, Guido Knopoff, Damian A. Lowengrub, John Twarock, Reidun Virgillito, Maria Enrica
author_facet	Bellomo, Nicola Bingham, Richard Chaplain, Mark A. J. Dosi, Giovanni Forni, Guido Knopoff, Damian A. Lowengrub, John Twarock, Reidun Virgillito, Maria Enrica
author_sort	Bellomo, Nicola
title	A multiscale model of virus pandemic: Heterogeneous interactive entities in a globally connected world
title_short	A multiscale model of virus pandemic: Heterogeneous interactive entities in a globally connected world
title_full	A multiscale model of virus pandemic: Heterogeneous interactive entities in a globally connected world
title_fullStr	A multiscale model of virus pandemic: Heterogeneous interactive entities in a globally connected world
title_full_unstemmed	A multiscale model of virus pandemic: Heterogeneous interactive entities in a globally connected world
title_sort	multiscale model of virus pandemic: heterogeneous interactive entities in a globally connected world
publisher	World Scientific
publishDate	2020
url	https://doi.org/10.1142/S0218202520500323 http://hdl.handle.net/11086/16280
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A multiscale model of virus pandemic: Heterogeneous interactive entities in a globally connected world

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