Risk genes in head and neck cancer: a systematic review and meta-analysis of last 5 years

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Head and Neck Carcinoma (HNC), of which the majority are squamous cell carcinomas of the head and neck (SCCHN), is the sixth most prevalent cancers in mankind and, presents high morbidity and low rates of survival.1 It is known that the apoptotic and proliferation genes are involved in cancer develo...

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Autores principales: Brunotto, M., Zarate, AM., Bono, A., Barra, JL., Berra, S.
Formato: article
Lenguaje:Inglés
Publicado: 2017
Materias:
Cáncer de Cabeza y Cuello
Patología Bucal
Revisión de Múltiples Casos
Revisión Sistemática
Diagnóstico Temprano
Acceso en línea:http://hdl.handle.net/11086/5502
Aporte de:
Repositorio Digital Universitario (UNC) de Universidad Nacional de Córdoba
id I10-R141-11086-5502
record_format dspace
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-141
collection Repositorio Digital Universitario (UNC)
language Inglés
topic Cáncer de Cabeza y Cuello
Patología Bucal
Revisión de Múltiples Casos
Revisión Sistemática
Diagnóstico Temprano
spellingShingle Cáncer de Cabeza y Cuello
Patología Bucal
Revisión de Múltiples Casos
Revisión Sistemática
Diagnóstico Temprano
Brunotto, M.
Zarate, AM.
Bono, A.
Barra, JL.
Berra, S.
Risk genes in head and neck cancer: a systematic review and meta-analysis of last 5 years
topic_facet Cáncer de Cabeza y Cuello
Patología Bucal
Revisión de Múltiples Casos
Revisión Sistemática
Diagnóstico Temprano
description Head and Neck Carcinoma (HNC), of which the majority are squamous cell carcinomas of the head and neck (SCCHN), is the sixth most prevalent cancers in mankind and, presents high morbidity and low rates of survival.1 It is known that the apoptotic and proliferation genes are involved in cancer development and these could be useful as a biomarker of this pathology. Systematic reviews and meta-analysis allow stronger and more generalized conclusions for identifying some models of risk markers. These models may help in screening, early diagnosis and/or therapy in the clinic.2-5 In recent decades, there has been increased interest in genetic predisposition studies in complex disease. This has led to the production of an enormous number of epidemiologic papers about the relationship between genetic polymorphism and disease. However, the magnitude of association between specific polymorphism and disease is still not established. The identification of a predictive model of risk polymorphisms could help in early diagnosis, and in understanding disease recurrence and/or progression in the subset of patients
format article
author Brunotto, M.
Zarate, AM.
Bono, A.
Barra, JL.
Berra, S.
author_facet Brunotto, M.
Zarate, AM.
Bono, A.
Barra, JL.
Berra, S.
author_sort Brunotto, M.
title Risk genes in head and neck cancer: a systematic review and meta-analysis of last 5 years
title_short Risk genes in head and neck cancer: a systematic review and meta-analysis of last 5 years
title_full Risk genes in head and neck cancer: a systematic review and meta-analysis of last 5 years
title_fullStr Risk genes in head and neck cancer: a systematic review and meta-analysis of last 5 years
title_full_unstemmed Risk genes in head and neck cancer: a systematic review and meta-analysis of last 5 years
title_sort risk genes in head and neck cancer: a systematic review and meta-analysis of last 5 years
publishDate 2017
url http://hdl.handle.net/11086/5502
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