Human Papillomavirus (HPV) in Oral Cavity Lesions: Comparison with Other Oral Cancer Risk Factors

Human papillomavirus (HPV) is considered a necessary factor for the development of cervical cancer; however, its relationship with oral cancer is controversial. The aim of this study was detect the presence of HPV in lesions of the oral cavity and its correlation with other risk factors. Presenc...

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Autores principales: Venezuela, Raúl Fernando, Talavela, Ángel, Frutos, María Cecilia, Keguen, Ana Ximena, Monetti, Marina Soledad, Sollazo, María, Panico, René, Ferreyra de Prato, Ruth, Cuffini, Cecilia Gabriela
Formato: article
Lenguaje:Inglés
Publicado: 2019
Materias:
HPV
Oral cavity lesions
Argentina
Lesión oral
Virus del papiloma humano
Acceso en línea:http://hdl.handle.net/11086/13488
Aporte de:
Repositorio Digital Universitario (UNC) de Universidad Nacional de Córdoba
id I10-R141-11086-13488
record_format dspace
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-141
collection Repositorio Digital Universitario (UNC)
language Inglés
topic HPV
Oral cavity lesions
Argentina
Lesión oral
Virus del papiloma humano
spellingShingle HPV
Oral cavity lesions
Argentina
Lesión oral
Virus del papiloma humano
Venezuela, Raúl Fernando
Talavela, Ángel
Frutos, María Cecilia
Keguen, Ana Ximena
Monetti, Marina Soledad
Sollazo, María
Panico, René
Ferreyra de Prato, Ruth
Cuffini, Cecilia Gabriela
Human Papillomavirus (HPV) in Oral Cavity Lesions: Comparison with Other Oral Cancer Risk Factors
topic_facet HPV
Oral cavity lesions
Argentina
Lesión oral
Virus del papiloma humano
description Human papillomavirus (HPV) is considered a necessary factor for the development of cervical cancer; however, its relationship with oral cancer is controversial. The aim of this study was detect the presence of HPV in lesions of the oral cavity and its correlation with other risk factors. Presence of HPV was studied by polymerase chain reaction in samples from benign lesions, potentially malignant lesions (PML), neoplasias and healthy mucosae. The results from the different groups were compared; in addition to their histopathological variables with tobacco smoking, alcohol consumption, so on. HPV was detected in 88.89% of benign lesions, 41.38% of PML and 56.25% of neoplasias. The most prevalent genotypes were 16 and 6. Together, reached 55% of the total number of cases. A significant association was observed between HPV and male gender, tobacco smokers, alcohol drinkers and benign lesions. Tobacco smoking and alcohol intake were associated to neoplasias. Our results showed that factors like tobacco smoking and alcohol drinking, have more influence than HPV in the development of oral neoplasias; however, 56.2% of the neoplasias tested positive for HPV; the percentage of HR-HPV detection increased with the severity of the lesions, suggesting its possible involvement in malignant processes
format article
author Venezuela, Raúl Fernando
Talavela, Ángel
Frutos, María Cecilia
Keguen, Ana Ximena
Monetti, Marina Soledad
Sollazo, María
Panico, René
Ferreyra de Prato, Ruth
Cuffini, Cecilia Gabriela
author_facet Venezuela, Raúl Fernando
Talavela, Ángel
Frutos, María Cecilia
Keguen, Ana Ximena
Monetti, Marina Soledad
Sollazo, María
Panico, René
Ferreyra de Prato, Ruth
Cuffini, Cecilia Gabriela
author_sort Venezuela, Raúl Fernando
title Human Papillomavirus (HPV) in Oral Cavity Lesions: Comparison with Other Oral Cancer Risk Factors
title_short Human Papillomavirus (HPV) in Oral Cavity Lesions: Comparison with Other Oral Cancer Risk Factors
title_full Human Papillomavirus (HPV) in Oral Cavity Lesions: Comparison with Other Oral Cancer Risk Factors
title_fullStr Human Papillomavirus (HPV) in Oral Cavity Lesions: Comparison with Other Oral Cancer Risk Factors
title_full_unstemmed Human Papillomavirus (HPV) in Oral Cavity Lesions: Comparison with Other Oral Cancer Risk Factors
title_sort human papillomavirus (hpv) in oral cavity lesions: comparison with other oral cancer risk factors
publishDate 2019
url http://hdl.handle.net/11086/13488
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