Antipsychotic prescription prevalence and metabolic monitoring of patients under chronic treatment

Introduction: Antipsychotics agents increase morbidity and mortality due to their metabolic impact. Information on its prescription and follow-up is scarce. The objective of this study was to estimate the chronic antipsychotic prescription prevalence and to evaluate the metabolic monitoring of patie...

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Autores principales: Vivacqua, María Noelia, Abudarham, Tomás, Pagotto, Vanina, Faccioli, José Luis
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2021
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Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/32653
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institution Universidad Nacional de Córdoba
institution_str I-10
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container_title_str Revistas de la UNC
language Español
format Artículo revista
topic antipsychotic agents
prevalence
aged
monitoring
antipsicóticos
prevalencia
ancianos
monitoreo
antipsicóticos
prevalência
idosos
monitoramento
spellingShingle antipsychotic agents
prevalence
aged
monitoring
antipsicóticos
prevalencia
ancianos
monitoreo
antipsicóticos
prevalência
idosos
monitoramento
Vivacqua, María Noelia
Abudarham, Tomás
Pagotto, Vanina
Faccioli, José Luis
Antipsychotic prescription prevalence and metabolic monitoring of patients under chronic treatment
topic_facet antipsychotic agents
prevalence
aged
monitoring
antipsicóticos
prevalencia
ancianos
monitoreo
antipsicóticos
prevalência
idosos
monitoramento
author Vivacqua, María Noelia
Abudarham, Tomás
Pagotto, Vanina
Faccioli, José Luis
author_facet Vivacqua, María Noelia
Abudarham, Tomás
Pagotto, Vanina
Faccioli, José Luis
author_sort Vivacqua, María Noelia
title Antipsychotic prescription prevalence and metabolic monitoring of patients under chronic treatment
title_short Antipsychotic prescription prevalence and metabolic monitoring of patients under chronic treatment
title_full Antipsychotic prescription prevalence and metabolic monitoring of patients under chronic treatment
title_fullStr Antipsychotic prescription prevalence and metabolic monitoring of patients under chronic treatment
title_full_unstemmed Antipsychotic prescription prevalence and metabolic monitoring of patients under chronic treatment
title_sort antipsychotic prescription prevalence and metabolic monitoring of patients under chronic treatment
description Introduction: Antipsychotics agents increase morbidity and mortality due to their metabolic impact. Information on its prescription and follow-up is scarce. The objective of this study was to estimate the chronic antipsychotic prescription prevalence and to evaluate the metabolic monitoring of patients treated with these medications.  Methods: We examined a retrospective cohort of patients older than 18 years treated in the outpatient setting of a hospital in Argentina. The crude and adjusted prevalence of chronic antipsychotic prescription was estimated by indirect standardization of the World Health Organization population, with its confidence interval (95%). It was evaluated whether the patients had biochemical determinations, systolic blood pressure (SBP), and body mass index (BMI) at the beginning and at 12 months of their treatment. Results: The crude antipsychotic prescription prevalence was 23.8 ‰ (95% CI 23.0 - 24.6) and the adjusted prevalence was 10.1 ‰ (95% CI 9.5-10.7). 3702 patients were evaluated. The male:female ratio was 0.6. Median age 77.5 years (IQR 25-75: 59.5-86.1). Quetiapine was the most frequently prescribed. Initial determinations: Lipid profile 1804 (48.7%), blood glucose 2034 (54.9%), SBP 2546 (68.8%) and BMI 1584 (42.8%). At 12 months: Lipid profile 680 (18.4%), blood glucose 898 (24.3%), SAT 1609 (43.5%), and BMI 1584 (21.7%).  Conclusions: We observed a higher prevalence of atypical antipsychotic prescription in the elderly and female population and scarce registry of biochemical determinations for adverse effects follow-up.   
publisher Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2021
url https://revistas.unc.edu.ar/index.php/med/article/view/32653
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