Vitamin D deficiency and osteoporosis en a rural population of Cordoba province, Argentina
Introduction: Vitamin D deficiency is defined when blood levels of 25-hydroxyvitamin D (25 (OH) D) is less than 20 ng / mmol/L. The status of Vitamin D level is associated with clinical, pathological and physiological changes as increased of parathyroid hormone, bone remodeling, osteoporosis and inc...
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| Autores principales: | , , , , , |
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| Formato: | Artículo revista |
| Lenguaje: | Español |
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Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2009
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| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/23461 |
| Aporte de: |
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I10-R10article-23461 |
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ojs |
| institution |
Universidad Nacional de Córdoba |
| institution_str |
I-10 |
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R-10 |
| container_title_str |
Revistas de la UNC |
| language |
Español |
| format |
Artículo revista |
| topic |
deficiencia de vitamina D osteoporosis población rural vitamin D deficiency osteoporosis rural populations |
| spellingShingle |
deficiencia de vitamina D osteoporosis población rural vitamin D deficiency osteoporosis rural populations Gobbi, C. Salica, D. Pepe, G. Petenian, E. Dotto, G. Martinez, F. Vitamin D deficiency and osteoporosis en a rural population of Cordoba province, Argentina |
| topic_facet |
deficiencia de vitamina D osteoporosis población rural vitamin D deficiency osteoporosis rural populations |
| author |
Gobbi, C. Salica, D. Pepe, G. Petenian, E. Dotto, G. Martinez, F. |
| author_facet |
Gobbi, C. Salica, D. Pepe, G. Petenian, E. Dotto, G. Martinez, F. |
| author_sort |
Gobbi, C. |
| title |
Vitamin D deficiency and osteoporosis en a rural population of Cordoba province, Argentina |
| title_short |
Vitamin D deficiency and osteoporosis en a rural population of Cordoba province, Argentina |
| title_full |
Vitamin D deficiency and osteoporosis en a rural population of Cordoba province, Argentina |
| title_fullStr |
Vitamin D deficiency and osteoporosis en a rural population of Cordoba province, Argentina |
| title_full_unstemmed |
Vitamin D deficiency and osteoporosis en a rural population of Cordoba province, Argentina |
| title_sort |
vitamin d deficiency and osteoporosis en a rural population of cordoba province, argentina |
| description |
Introduction: Vitamin D deficiency is defined when blood levels of 25-hydroxyvitamin D (25 (OH) D) is less than 20 ng / mmol/L. The status of Vitamin D level is associated with clinical, pathological and physiological changes as increased of parathyroid hormone, bone remodeling, osteoporosis and increased risk of fractures. Moreover, vitamin D and its metabolites are known to be associated with multiple chronic diseases as diabetes mellitus, autoimmune, cardiovascular and neoplasia diseases. Objective: To assess the vitamin D status in a rural population of Córdoba Province in Argentina and its relation with bone mineral density. Material and Methods: We prospectively studied 31 patients over 50 years old who live in a rural population of Pampa de Achala in Córdoba Province, Argentina. This city is located in Córdoba High mountains. Blood vitamin D levels were tested in 24 patients and Bone mineral density in 31 patients. Vitamin D level was determined by HPLC. The vitamin D level were considered normal between 20-50 ng/ml in the winter season and 20-80 ng/ml in the summer season. Bone mineral density of lumbar spine and femoral neck was measured by DXA GE LUNAR DPX-L, according to World Health organization classification (37). The data were analyzed by Spearman coeficient and Chi cuadrado.Results: The vitamin D levels samples were avaliable in 24 patients. Mean blood Vitamin D level was 24.54 ng /ml. 8 of them (33%) had vitamin D level less than 20ng/ ml. 83% (20) of the analysed patients had vitamin D level less than 30 ng/ml and only 4 patients has vitamin D level more than 30 ng/ml.Low bone mineral density of lumbar spine and femoral neck was found in 66 % of the patients. 19 % of the patients were diagnosed of lumbar spine and femoral neck osteoporosis and 29% of them had lumbar spine meanwhile 25% had femoral neck. There was not statistically significant associaton between vitamin D level and bone mineral density analysed by Chi Cuadrado (p<0.07). A significant association was found between blood vitamin D level and low bone mineral density of femoral neck (Spearman 0.51) Conclusions: Vitamin D insufficiency is high in the rural adult population of Pampa de Achala in Córdoba and it could be a major health problem in this population. |
| publisher |
Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2009 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/23461 |
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