Analysis of the decrease in deaths due to coronary disease between 1995 and 2010. IMPACT CHD Argentina Study

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Objective: To quantify the contribution of risk factors and treatments in the reduction of mortality due to coronary heart disease in Argentina between 1995 and 2010.Methods: We used the validated IMPACTCHD model integrating data on effectiveness, use of treatments and changes in the risk factors be...

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Autores principales: Vicens, Jimena, Perman, Gastón, Aliperti, Valeria, Masson, Walter, Schargrodsky, Herman, Pramparo, Palmira, Ferrante, Daniel, Figar, Silvana, Capewell, Simon, O’Flaherty, Martín
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2019
Materias:
coronary disease
risk factors
therapeutics
mortality
epidemiology
enfermedad coronaria
factores de riesgo
terapéutica
mortalidad
epidemiología.
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/22915
Aporte de:
Revistas de la UNC de Universidad Nacional de Córdoba
id I10-R10article-22915
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institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-10
container_title_str Revistas de la UNC
language Español
format Artículo revista
topic coronary disease
risk factors
therapeutics
mortality
epidemiology
enfermedad coronaria
factores de riesgo
terapéutica
mortalidad
epidemiología.
spellingShingle coronary disease
risk factors
therapeutics
mortality
epidemiology
enfermedad coronaria
factores de riesgo
terapéutica
mortalidad
epidemiología.
Vicens, Jimena
Perman, Gastón
Aliperti, Valeria
Masson, Walter
Schargrodsky, Herman
Pramparo, Palmira
Ferrante, Daniel
Figar, Silvana
Capewell, Simon
O’Flaherty, Martín
Analysis of the decrease in deaths due to coronary disease between 1995 and 2010. IMPACT CHD Argentina Study
topic_facet coronary disease
risk factors
therapeutics
mortality
epidemiology
enfermedad coronaria
factores de riesgo
terapéutica
mortalidad
epidemiología.
author Vicens, Jimena
Perman, Gastón
Aliperti, Valeria
Masson, Walter
Schargrodsky, Herman
Pramparo, Palmira
Ferrante, Daniel
Figar, Silvana
Capewell, Simon
O’Flaherty, Martín
author_facet Vicens, Jimena
Perman, Gastón
Aliperti, Valeria
Masson, Walter
Schargrodsky, Herman
Pramparo, Palmira
Ferrante, Daniel
Figar, Silvana
Capewell, Simon
O’Flaherty, Martín
author_sort Vicens, Jimena
title Analysis of the decrease in deaths due to coronary disease between 1995 and 2010. IMPACT CHD Argentina Study
title_short Analysis of the decrease in deaths due to coronary disease between 1995 and 2010. IMPACT CHD Argentina Study
title_full Analysis of the decrease in deaths due to coronary disease between 1995 and 2010. IMPACT CHD Argentina Study
title_fullStr Analysis of the decrease in deaths due to coronary disease between 1995 and 2010. IMPACT CHD Argentina Study
title_full_unstemmed Analysis of the decrease in deaths due to coronary disease between 1995 and 2010. IMPACT CHD Argentina Study
title_sort analysis of the decrease in deaths due to coronary disease between 1995 and 2010. impact chd argentina study
description Objective: To quantify the contribution of risk factors and treatments in the reduction of mortality due to coronary heart disease in Argentina between 1995 and 2010.Methods: We used the validated IMPACTCHD model integrating data on effectiveness, use of treatments and changes in the risk factors between 1995 and 2010 in people older than 25 years in Argentina. The difference between the coronary deaths observed and expected in 2010 was distributed between treatments and risk factors.Results: Between 1995 and 2010, adjusted mortality rates for coronary heart disease decreased 29.8% (8,500 deaths prevented or postponed - MPP). Improvements in treatments accounted for 49.9%, mostly secondary prevention of acute myocardial infarction (8.2%); antihypertensive treatment (11.9%) and treatment of heart failure (13.2%). Improvements in risk factors accounted for 32.9% of MPPs: systolic blood pressure 34.6%; total cholesterol 12.8%; smoking 6.8%. An excess of deaths was found due to the increase in diabetes (9.4%), obesity (6.9%) and sedentary lifestyle (5%). The 17.2% of the MPPs were not explained by the model.Conclusion: One out of every two MPP due to coronary heart disease in Argentina between 1995 and 2010 was due to treatments and one third to the improvement of risk factors. The decrease in blood pressure, cholesterol and smoking was limited by increases in the prevalence of obesity, sedentary lifestyle and diabetes. This study was possible thanks to the collaborative work to the cardiovascular epidemiology.
publisher Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2019
url https://revistas.unc.edu.ar/index.php/med/article/view/22915
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