Effects of molybdenosis on luteinizing hormone, follicle stimulating and estradiol hormones in rats

This work studies the effect of molybdenum on estrous activity and reproductive hormones: LH, FSH and estradiol. Twenty one Wistar weanling female rats were assigned to three experimental groups, A: Control, B: Copper deficiency and C: Molybdenum toxicity. All groups were fed with 70% cow milk (1 pp...

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Autor principal: Igarza, L.
Otros Autores: Agostini, M., Becú-Villalobos, D., Auza, N.
Formato: Capítulo de libro
Lenguaje:Español
Publicado: 1996
Acceso en línea:Registro en Scopus
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Registro en la Biblioteca Digital
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100 1 |a Igarza, L. 
245 1 0 |a Effects of molybdenosis on luteinizing hormone, follicle stimulating and estradiol hormones in rats 
246 3 1 |a Efectos de la molibdenosis sobre hormona luteinizante, folículo estimulante y estradiol en ratas 
260 |c 1996 
270 1 0 |m Igarza, L.; Dpto. de Fisiopatología, Facultad de Ciencias Veterinarias, Univ. Nac. Centra de la Peia Buenos, Pinto 399, Tandil 7000, Argentina 
506 |2 openaire  |e Política editorial 
504 |a Allen, K.G.D., Klevay, L.M., Copper deficiency and cholesterol metabolism in the rat (1978) Atherosclerosis, 3, pp. 271-276 
504 |a Auza, N., (1983) Contribution a L'étude de La Distribution et de La Toxicite du Cuivre et du Molybdene Chez le Rat, La Souris et le Mouton, pp. 27-119. , Thèse, l'Institut National Polytechnique de Toulose 
504 |a Benard, P., Auza, N., Transplacental passage of 99Molybdenum in rats and ewes wholebody autoradiographic study (1986) Proc. Royal Microsc. Soc., 21, pp. 287-288 
504 |a Diaz-Torga, G., Becu-Villalobos, D., Lacau De Mengido, I.M., Libertun, C., Sexual and ontogenic differences in Kt-induced gonadotropin and prolactin release in vitro (1992) Develop. Brain Res., 70, pp. 103-108 
504 |a Freeman, M.E., The ovarian cycle of the rat (1988) The Physiology of Reproduction, , E. KNOBILAND, J. NEIL. Raven Press, Ltd. New York 
504 |a Fungwe, T.V., Buddingh, C.D., Yang, M.T., Yang, S.P., Effect of dietary Molybdenum supplementation on reproduction in the female Sprague-Dawley rats (1986) J. Nutr., 116, pp. xxxvi. , abs. 95 
504 |a Fungwe, T.V., Buddingh, F., Lox, C.D., Yang, M.T., Yang, S.P., Molybdenum and copper enzimes and hormone activity in molybdenum supplemented female rats (1987) Fed. Proceed., 46, p. 755 
504 |a Fungwe, T.V., Buddingh, C.D., Demick, D.S., Lox, C.D., Yang, M.T., Yang, S.P., The role of dietary molybdenum on estrous activity, fertility, reproduction and molybdenum and copper enzyme activities of female rats (1990) Nutr. Res., 10, pp. 515-524 
504 |a Igarza, L., (1993) Molibdenosis Experimental en Ratas y Ovinos, , Tesis, Universidad Nacional de Mar del Plata, Escuela de Postgrado, Facultad de Ciencias Agrarias, Balcarce, Argentina 
504 |a Koremam, S.G., Stevens, R.H., Carpenter, L.A., Robe, M., Niswender, G.H., Sherman, B.M., Estradiol radioimmunoassay without chromatography, procedure validation and normal values (1974) J. Clin. Endocrinol. Metabolism, 38, pp. 718-720 
504 |a Long, J.A., Evans, H.M., (1922) Memories Univ. Calif., 6, p. 1 
504 |a Schwartz, N.B., (1969) Recent Prog. Horm. Res., 25 (3). , Ed. E.B. Astwood, Academic Press 
504 |a Lou, X.M., Wei, H.J., Yang, S.P., Inhibitory effects of molybdenum on esophageal and forestomach carcinogenesis in rats (1983) JNCI., 71, pp. 75-81 
504 |a Moffor, P.M., Rodway, R.G., The effect of tetrathiomolybdate on growth rate and onset of puberty in ewe-lambs (1991) Br. Vet. J., 147, pp. 421-431 
504 |a Nederbragt, H., The influence of molybdenum on the copper metabolism of the rat at different Cu levels of the diet (1980) Dr. J. Nutr., 43, pp. 329-338 
504 |a Nederbragt, H., Van Den Hamer, C.J.A., Influence of dietary molybdenum on the metabolism of intravenously injected radioactive copper in the rat (1981) J. Inorg. Bioch., 15, pp. 281-291 
504 |a Niswender, G.D., Midgley, A.R., Monroe, S.E., Reichert, L.E., Radioimmunoassay for rat luteinizing hormone with antiovine LH serum and ovine LH-131-I (1968) Proc. Soc. Exp. Biol. Med., 128, pp. 807-812 
504 |a Phillippo, M., Humphiries, W.R., Atkinson, T., The effect of molybdenum on fertility in the cow (1985) Proc. Nutr. Soc., 44, pp. 82A 
504 |a Phillippo, M., Humphiries, W.R., Garthwaite, P.H., The effect of dietary molybdenum and iron on copper status and growth in cattle (1987) J. Agric. Sci. (Camb.), 109, pp. 315-320 
504 |a Prohaska, J.R., Biochemical changes in copper deficiency (1990) J. Nutr. Biochem., 1, pp. 452-461 
504 |a Rice, E.W., Normalization de la actividad ceruloplasmínica en términos de unidades enzimáticas internacionales. Formación oxidativa de base de Bandrowsky a partir de p-fenilenodiamina por la acción de la ceruloplasmina (1962) Anal Biochem., 3, pp. 452-456 
504 |a Winston, P.W., (1981) Molybdenum Disorders of Mineral Metabolism, 1, pp. 295-315. , New York. Academic Press 
504 |a Phillippo, M., Humphiries, W.R., Garthwaite, P.M., The effect of dietary molybdenum and iron on copper status and growth in cattle (1987) J. Agric. Sci. (Camb.), 109, pp. 315-320 
520 3 |a This work studies the effect of molybdenum on estrous activity and reproductive hormones: LH, FSH and estradiol. Twenty one Wistar weanling female rats were assigned to three experimental groups, A: Control, B: Copper deficiency and C: Molybdenum toxicity. All groups were fed with 70% cow milk (1 ppm Cu) and 30% corn meal (0.8 ppm Cu). They were supplemented for 60 days as follows: A: 40 ppm SO4 CU2 + 40 ppm SO4 Fe2, B: 40 ppm SO4 Fe2, C: 40 ppm SO4 Cu2 + 40 ppm SO4 Fe2 + 500 ppm Na2 Mo O4. Vaginal smears showed that high dietary Mo prolonged the length of the estrous cycle and altered the cytological characteristics of the different phases of the cycle. Peak values of FSH were significantly lower in molybdenotic animals. Serum E2 was lower both in the two deficient groups and in molybdenotic animals. In conclusion, high dietary Mo decreased the FSH levels although elevated Mo and copper deficiency decreased the levels of estradiol, different mechanisms could be involved. Changes in estrous cycle in molybdenotic animals may be subsequent to alteration in FSH and E2, secretion.  |l eng 
593 |a Dpto. de Fisiopatología, Facultad de Ciencias Veterinarias, Univ. Nac. Centra de la Peia Buenos, Pinto 399, Tandil 7000, Argentina 
593 |a Inst. de Biol. y Med. Experimental, CONICET, Obligado 2490, Buenos Aires 1428, Argentina 
690 1 0 |a ESTRADIOL 
690 1 0 |a ESTROUS CYCLE 
690 1 0 |a FSH 
690 1 0 |a LH 
690 1 0 |a MOLYBDENUM 
690 1 0 |a RATS 
700 1 |a Agostini, M. 
700 1 |a Becú-Villalobos, D. 
700 1 |a Auza, N. 
773 0 |d 1996  |g v. 28  |h pp. 101-106  |k n. 1  |p Arch. Med. Vet.  |x 0301732X  |w (AR-BaUEN)CENRE-3822  |t Archivos de Medicina Veterinaria 
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856 4 0 |u https://hdl.handle.net/20.500.12110/paper_0301732X_v28_n1_p101_Igarza  |y Handle 
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