Functional, pharmacological and morphological characteristics of two regions of rat uterine horns

A histological, physiological and pharmacological study of two regions of the isolated uterine muscle of the rat., connective myometrial myometrial one (a zone close to the mesometrial insertion) and the linea uteri (the antimesometrial zone) was performed. From the histological point of view the li...

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Detalles Bibliográficos
Autor principal: Borda, E.S
Otros Autores: Sterin-Borda, L., Sterin-Speziale, N., Gimeno, M.F, Gimeno, A.L
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 1978
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Acceso en línea:Registro en Scopus
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Registro en la Biblioteca Digital
Aporte de:Registro referencial: Solicitar el recurso aquí
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001 PAPER-18607
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024 7 |2 scopus  |a 2-s2.0-0018045441 
024 7 |2 cas  |a atropine, 51-55-8, 55-48-1; hemicholinium 3, 16478-59-4; oxytocin, 50-56-6, 54577-94-5; Acetylcholine, 51-84-3; Atropine, 51-55-8; Hemicholinium 3, 312-45-8; Oxytocin, 50-56-6 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
030 |a APLTA 
100 1 |a Borda, E.S. 
245 1 0 |a Functional, pharmacological and morphological characteristics of two regions of rat uterine horns 
260 |c 1978 
506 |2 openaire  |e Política editorial 
520 3 |a A histological, physiological and pharmacological study of two regions of the isolated uterine muscle of the rat., connective myometrial myometrial one (a zone close to the mesometrial insertion) and the linea uteri (the antimesometrial zone) was performed. From the histological point of view the linea uteri (LU) is characterized by the presence of small bundles of longitudinal smooth muscle fibers (20 to 50), closely packed and clearly surrounded by a connecvtive tissue, whereas in the myomterial zone (M) the smooth muscle fibers are less closely packed and the connective tissue surrounds a greater number of them. The spontaneous oxytocin or electrically-induced initial tension developed by the LU or the M, was similar. Also the stability with time did not differ between both regions. Atropine depressed consistently the isometric developed tension of M strips, either spontaneously active or driven by oxytocin or electrical stimulation, but had no action on the mechanical activity of preparations from the LU. A pretreatment with hemicholinium also inhibited the spontaneous as well as the oxytocin-induced motility of M strips, without affecting those of LU. Pharmacologic evidence suggests that acetylcholine may play a 'facilitating' role in M strips for the conduction of coordinate contractions. This does not appear to be the case in the LU, which has the required characteristics to be recognized as a conductive tissue.  |l eng 
593 |a Cent. Estud. Farmacol. Principios Naturales, Consejo Nac. Invest. Ci. Tecn., Republ. Argentina, Buenos Aires, Argentina 
690 1 0 |a ATROPINE 
690 1 0 |a HEMICHOLINIUM 3 
690 1 0 |a OXYTOCIN 
690 1 0 |a SYNTHOCINON 
690 1 0 |a UNCLASSIFIED DRUG 
690 1 0 |a ANIMAL EXPERIMENT 
690 1 0 |a FEMALE GENITAL SYSTEM 
690 1 0 |a HISTOLOGY 
690 1 0 |a MICROSCOPY 
690 1 0 |a MYOMETRIUM 
690 1 0 |a RAT 
690 1 0 |a UTERUS CONTRACTILITY 
690 1 0 |a UTERUS HORN 
690 1 0 |a ACETYLCHOLINE 
690 1 0 |a ANIMALS 
690 1 0 |a ATROPINE 
690 1 0 |a ELECTRIC STIMULATION 
690 1 0 |a FEMALE 
690 1 0 |a HEMICHOLINIUM 3 
690 1 0 |a MYOMETRIUM 
690 1 0 |a OXYTOCIN 
690 1 0 |a RATS 
690 1 0 |a RATS, INBRED STRAINS 
690 1 0 |a UTERINE CONTRACTION 
690 1 0 |a UTERUS 
653 0 0 |a synthocinon 
700 1 |a Sterin-Borda, L. 
700 1 |a Sterin-Speziale, N. 
700 1 |a Gimeno, M.F. 
700 1 |a Gimeno, A.L. 
773 0 |d 1978  |g v. 28  |h pp. 223-233  |k n. 6  |p ACTA PHYSIOL. LAT.-AM.  |t Acta Physiologica Latino-Americana 
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856 4 0 |u https://hdl.handle.net/20.500.12110/paper_NIS18607_v28_n6_p223_Borda  |y Handle 
856 4 0 |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_NIS18607_v28_n6_p223_Borda  |y Registro en la Biblioteca Digital 
961 |a paper_NIS18607_v28_n6_p223_Borda  |b paper  |c PE 
962 |a info:eu-repo/semantics/article  |a info:ar-repo/semantics/artículo  |b info:eu-repo/semantics/publishedVersion 
999 |c 79560