Spontaneous contractile activity of isolated ovarian human vein. A dual influence of prostacyclin (PGI2)
The profile of spontaneous contractions as well as the influences of prostacyclin (PGI2) on the motility of human ovarian veins obtained during the estrogenic phase of the sex cycle were explored. The preparations exhibited a distinct phasic activity, which progressively decreased as isolation time...
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| Otros Autores: | , , , |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
1979
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 07270caa a22008657a 4500 | ||
|---|---|---|---|
| 001 | PAPER-18581 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518204957.0 | ||
| 008 | 190411s1979 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0018610070 | |
| 024 | 7 | |2 cas |a phentolamine, 50-60-2, 73-05-2; propranolol, 13013-17-7, 318-98-9, 3506-09-0, 4199-09-1, 525-66-6; prostacyclin, 35121-78-9, 61849-14-7; Epoprostenol, 35121-78-9; Phentolamine, 50-60-2; Propranolol, 525-66-6; Prostaglandins | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a PRGLB | ||
| 100 | 1 | |a Borda, E.S. | |
| 245 | 1 | 0 | |a Spontaneous contractile activity of isolated ovarian human vein. A dual influence of prostacyclin (PGI2) |
| 260 | |c 1979 | ||
| 270 | 1 | 0 | |m Borda, E.S.; Centro de Estudios Farmacológicos y de Principios Naturales (CEFAPRIN), CONICET. V. de Obligado 2490., 1428 Buenos Aires, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Somlyo, Vascular smooth muscle (1968) I. Normal structure, pathology, biochemistry and biophysics, 20, pp. 197-272. , 2nd edit., Pharmacol.Rev | ||
| 504 | |a Czekanowski, Investigations into the spontaneous contractile activity of isolated human uterine arteries in vitro (1975) Am.J.Obstet.Gynec., 121, pp. 718-722 | ||
| 504 | |a Holman, Kasby, Suthers, Wilson, Some properties of the smooth muscle of rabbit portal vein (1968) J.Physiol.(London), 196, pp. 111-132 | ||
| 504 | |a Johansson, Ljung, Spread of excitation in the smooth muscle of the rat portal vein (1967) Acta Physiol.Scan., 70, pp. 312-322 | ||
| 504 | |a Nakajima, Horn, Electrical activity of single vascular smooth muscle fibers (1967) Am.J.Physiol., 213, pp. 25-30 | ||
| 504 | |a Moncada, Gryglewski, Bunting, Vane, An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation (1976) Nature, 263, pp. 663-665 | ||
| 504 | |a Dusting, Moncada, Vane, Prostacyclin (PGX) is the endogenous metabolite responsible for relaxation of coronary artery (1977) Prostaglandins, 13, pp. 3-16 | ||
| 504 | |a Pomerantz, Sintetos, Ramwell, The effect of prostacyclin on the human umbilical artery (1978) Prostaglandins, 15, pp. 1035-1044 | ||
| 504 | |a Chapleau, White, Effects of prostacyclin on the canine isolated baselar artery (1979) Prostaglandins, 17, pp. 573-580 | ||
| 504 | |a Gryglwski, Bunting, Moncada, Flower, Vane, Arterial wall are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides (1976) Prostaglandins, 12, pp. 685-713 | ||
| 504 | |a Gimeno, Borda, Sterin-Borda, Vidal, Gimeno, Pharmacological influences on human ovarian contractions (1976) Obstet.Gynecol., 47, pp. 218-222 | ||
| 504 | |a Moncada, Higgs, Vane, Human arterial and venous tissues generate prostacyclin (prostaglandin X) a potent inhibitor of platelet aggregation (1977) Lancet, 1, pp. 18-20 | ||
| 504 | |a Borda, Canga, Gimeno, Gimeno, Adrenergic mechanisms subserving a positive inotropism and chronotropism of prostacyclin on isolated rat atria (1979) Experientia, 35, pp. 529-531 | ||
| 504 | |a Toda, The action of vasodilating drugs on isolated basilar, coronary and mesenteric arteries of the dog (1974) J. Pharmac.Exptl.Therap., 191, pp. 139-146 | ||
| 504 | |a Herman, Verbeurens, Moncada, Vane, Vanhoutte, Effect of prostacyclin on myogenic activity and adrenergic neuroeffector interaction in isolated canine veins (1978) Arch.int.Pharmacodyn.Thér., 232, pp. 340-341 | ||
| 504 | |a Levi, Contractile responses to prostacyclin (PGI2) of isolated human saphenous and rat venous tissue (1978) Prostaglandins, 16, pp. 93-97 | ||
| 504 | |a Lamond, Drost, The counter current transfer of prostaglandin in the ewe (1973) Prostaglandins, 3, pp. 691-695 | ||
| 504 | |a McCracken, Einer-Jensen, The counter current transfer of progesterone in the ovarian vascular pedicle (1976) V.International Congress of Endocrinology, , Hamburg, Abstract No 775 | ||
| 504 | |a Bendz, The anatomical basis for a possible counter current exchange mechanism in the human adnex (1977) Prostaglandins, 13, pp. 355-362 | ||
| 520 | 3 | |a The profile of spontaneous contractions as well as the influences of prostacyclin (PGI2) on the motility of human ovarian veins obtained during the estrogenic phase of the sex cycle were explored. The preparations exhibited a distinct phasic activity, which progressively decreased as isolation time progresses, dissapearing almost completely following more than two hours. PGI2 produced a biphasic influence on quiescent preparations. After the threshold is attained lower concentrations caused depression of tone whereas higher ones enhanced the basal tone and induced phasic contractile cycles. Phentolamine reduced markedly the stimulating influence of PGI2 but had no action on the inhibitory effects, whereas propranolol failed to alter either the excitatory or the depressive action. The results suggest a participation of alpha-adrenoceptive-mediated mechanisms in the stimulatory effects of PGI2. On the other hand, PGI2 may be of importance in the regulation of venous flow and the spontaneous or PGI2-induced contractions could play a role in the counter current mechanism between veins and arteries in the ovarian pedicle. © 1980. |l eng | |
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas | ||
| 536 | |a Detalles de la financiación: (I) This work has been supported by Grant 6638 from the Cbn-aejo Nscional de Investigaciones Cientificas y T6cnicss (CONICET) de la Rep6blica Argentina. | ||
| 593 | |a Centro de Estudios Farmacológicos y de Principios Naturales (CEFAPRIN), CONICET. V. de Obligado 2490., 1428 Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a PHENTOLAMINE |
| 690 | 1 | 0 | |a PROPRANOLOL |
| 690 | 1 | 0 | |a PROSTACYCLIN |
| 690 | 1 | 0 | |a ESTRUS |
| 690 | 1 | 0 | |a HUMAN |
| 690 | 1 | 0 | |a HUMAN CELL |
| 690 | 1 | 0 | |a IN VITRO STUDY |
| 690 | 1 | 0 | |a MUSCLE CONTRACTILITY |
| 690 | 1 | 0 | |a NORMAL HUMAN |
| 690 | 1 | 0 | |a OVARIAN VEIN |
| 690 | 1 | 0 | |a PERIPHERAL VASCULAR SYSTEM |
| 690 | 1 | 0 | |a VENOCONSTRICTION |
| 690 | 1 | 0 | |a ADULT |
| 690 | 1 | 0 | |a EPOPROSTENOL |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a HUMANS |
| 690 | 1 | 0 | |a MUSCLE CONTRACTION |
| 690 | 1 | 0 | |a OVARY |
| 690 | 1 | 0 | |a PHENTOLAMINE |
| 690 | 1 | 0 | |a PROPRANOLOL |
| 690 | 1 | 0 | |a PROSTAGLANDINS |
| 690 | 1 | 0 | |a VEINS |
| 700 | 1 | |a Agostini, M.C. | |
| 700 | 1 | |a Sterin-Speziale, N. | |
| 700 | 1 | |a Gimeno, M.F. | |
| 700 | 1 | |a Gimeno, A.L. | |
| 773 | 0 | |d 1979 |g v. 18 |h pp. 829-835 |k n. 6 |p Prostaglandins |x 00906980 |t Prostaglandins | |
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| 856 | 4 | 0 | |u https://doi.org/10.1016/0090-6980(79)90120-5 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_00906980_v18_n6_p829_Borda |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00906980_v18_n6_p829_Borda |y Registro en la Biblioteca Digital |
| 961 | |a paper_00906980_v18_n6_p829_Borda |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 999 | |c 79534 | ||