Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle
Measurements were made of spontaneous contractions and release of prostaglandin E-and F-like material into the bathing medium by uterine horns isolated from rats in different stages of the sex cycle. After 70 min of contractile activity the preparations from estrous rats released more PGF than those...
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| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
1981
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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| LEADER | 07017caa a22008297a 4500 | ||
|---|---|---|---|
| 001 | PAPER-18478 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518204950.0 | ||
| 008 | 190411s1981 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0019772149 | |
| 024 | 7 | |2 cas |a prostaglandin E, 11042-70-9; Epoprostenol, 35121-78-9; Prostaglandins; Prostaglandins E; Prostaglandins F | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a PRGLB | ||
| 100 | 1 | |a Franchi, A.M. | |
| 245 | 1 | 0 | |a Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle |
| 260 | |c 1981 | ||
| 270 | 1 | 0 | |m Franchi, A.M.; Centro de Estudios Farmocológicos y de Principios Naturales (CEFAPRIN), V. de Obligado 2490, 1428 Buenos Aires, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Sharma, Garg, Measurement of prostaglandins E and F in the uterine tissue and uterine fluid of ovariectomized rats treated with various doses of oestradiol-17 (1977) J. Reprod. Fert., 51, pp. 119-121 | ||
| 504 | |a Van Orden, Goodale, Baker, Barley, Bhatnager, Uterine Catecholamines and Prostaglandinis during the Estrous Cycle of the Rat (1980) Endocrinol., 106, pp. 1650-1654 | ||
| 504 | |a Poyser, Scott, Prostaglandin and thromboxane production by the rat uterus and ovary in vitro during the oestrous cycle (1980) J. Reprod. Fert., 60, pp. 33-40 | ||
| 504 | |a Ham, Cirillo, Zanetti, Kuehl, Estrogen-directed synthesis of specific prostaglandins in uterus (1975) Proc. Natn. Acad. Sci. USA, 72, pp. 1420-1429 | ||
| 504 | |a Downing, Williams, Differential prostaglandin production by microsomal fractions fo rat pregnant uterus (1977) Brit. J. Pharmacol., 61, p. 158p | ||
| 504 | |a Saksena, Shaikh, Shaikh, Uterine and peripheral plasma F-prostaglandins correlated with peripheral progesterone in cyclic rats (1973) Prostaglandins, 4, pp. 243-249 | ||
| 504 | |a Vane, Williams, The contribution of prostaglandin production to contractions of the isolated uterus of the rat (1973) Brit. J. Pharmacol., 48, pp. 629-639 | ||
| 504 | |a Harney, Sneddon, Williams, The influence of ovarian hormones upon the motility and prostaglandin production of the pregnant rat uterus in vitro (1974) J. Endocrinol., 60, pp. 343-351 | ||
| 504 | |a Dubin, Ghodgaonkar, King, Role of Prostaglandin Production in Spontaneous and Oxytocin-Induced Uterine Contractile Activity in, “in vitro” Pregnant rat Uteri (1979) Endocrinology, 105, p. 47 | ||
| 504 | |a Gimeno, Sterin-Speziale, Landa, Bonacossa, Gimeno, Is the spontaneous motility of isolated rat uterus controlled by Prostaglandin E? (1979) Prostaglandinss, 17, pp. 673-683 | ||
| 504 | |a Sterin-Speziale, Gimeno, Bonacossa, Gimeno, The effect of estradiol on isolated rat uterine motility and on prostaglandin generation (1980) Prostaglandins, 20, pp. 233-243 | ||
| 504 | |a Gimeno, Borda, Sterin-Borda, Vidal, Gimeno, Pharmacologic influences on human ovarian contractions (1976) Obstet. Gynec. (N.Y.), 47, pp. 218-222 | ||
| 504 | |a Vane, The use of isolated organs for detection active substance in the circulatory blood (1964) Brit. J. Pharmacol. Chemother., 23, pp. 360-367 | ||
| 504 | |a Gilmore, Vane, Willie, Prostaglandins released by the spleen (1968) Nature, 218, pp. 135-137 | ||
| 504 | |a Gimeno, Borda, Lazzari, Gimeno, Ovarian hormones inhibit the release of prostacyclin like material from isolated rat uterus (1980) Prostaglandins, 20, pp. 223-232 | ||
| 520 | 3 | |a Measurements were made of spontaneous contractions and release of prostaglandin E-and F-like material into the bathing medium by uterine horns isolated from rats in different stages of the sex cycle. After 70 min of contractile activity the preparations from estrous rats released more PGF than those from proestrous or metestrous rats. On the other hand, similar amounts of PGF-like material is generated by estrous and diestrous horns. Less PGE-like material was found in the bathing solution during estrus than in metestrus or diestrus; the values obtained during proestrus were similar to those in estrus. PGI2_like material produced by chopped uterine tissue was greater during diestrus than in estrus. The initial isometric developed tension (IDT) and tension constancy varied depeding of the stage of the sex cycle. Uteri from metestrous rats exhibited greater IDT and less % change with time than preparations from estrous or proestrous rats. The initial IDT, the tension change with time and contractile frequency correlate with the PGE-like material in the bathing solution during the 4 days of the sex cycle. There was no correlation with PGF-like material. © 1979. |l eng | |
| 536 | |a Detalles de la financiación: The capacity of the non-pregnant rat uterus to synthetize prostaglandins (PGs) has been studied in homogenized tissues (1,2,3), in uterine microsomal fractions (4,5) and in peripheral plasma (6). In general there are few reports measuring the PGs in relation to myometrial spontaneous motility. Vane and Williams (71, Hardney et al. (8) and Dubin et al. (9) observed an apparent relationship between phasic spontaneous contractions and (I) This work has been supported by Grant 6638 from the Consejo National de Investigaciones Cientificas y Thcnicas (CONICET) de la RepAblica Argentina. | ||
| 593 | |a Centro de Estudios Farmocológicos y de Principios Naturales (CEFAPRIN), V. de Obligado 2490, 1428 Buenos Aires, Argentina | ||
| 593 | |a Instituto de Investigaciones Hematológicas, Argentina | ||
| 690 | 1 | 0 | |a PROSTAGLANDIN |
| 690 | 1 | 0 | |a PROSTAGLANDIN E |
| 690 | 1 | 0 | |a PROSTAGLANDIN F |
| 690 | 1 | 0 | |a ANIMAL EXPERIMENT |
| 690 | 1 | 0 | |a ESTRUS |
| 690 | 1 | 0 | |a FEMALE GENITAL SYSTEM |
| 690 | 1 | 0 | |a MYOMETRIUM |
| 690 | 1 | 0 | |a RAT |
| 690 | 1 | 0 | |a UTERUS HORN |
| 690 | 1 | 0 | |a ANIMALS |
| 690 | 1 | 0 | |a EPOPROSTENOL |
| 690 | 1 | 0 | |a ESTRUS |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a PREGNANCY |
| 690 | 1 | 0 | |a PROSTAGLANDINS |
| 690 | 1 | 0 | |a PROSTAGLANDINS E |
| 690 | 1 | 0 | |a PROSTAGLANDINS F |
| 690 | 1 | 0 | |a RATS |
| 690 | 1 | 0 | |a RATS, INBRED STRAINS |
| 690 | 1 | 0 | |a UTERINE CONTRACTION |
| 690 | 1 | 0 | |a UTERUS |
| 690 | 1 | 0 | |a ANIMALIA |
| 700 | 1 | |a Chaud, M. | |
| 700 | 1 | |a Borda, E.S. | |
| 700 | 1 | |a Gimeno, M.F. | |
| 700 | 1 | |a Lazzari, M.A. | |
| 700 | 1 | |a Gimeno, A.L. | |
| 773 | 0 | |d 1981 |g v. 22 |h pp. 637-649 |k n. 4 |p Prostaglandins |x 00906980 |t Prostaglandins | |
| 856 | 4 | 1 | |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019772149&doi=10.1016%2f0090-6980%2881%2990073-3&partnerID=40&md5=c59882ec01733c2d4040ca19f2c2cfe7 |y Registro en Scopus |
| 856 | 4 | 0 | |u https://doi.org/10.1016/0090-6980(81)90073-3 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_00906980_v22_n4_p637_Franchi |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00906980_v22_n4_p637_Franchi |y Registro en la Biblioteca Digital |
| 961 | |a paper_00906980_v22_n4_p637_Franchi |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 999 | |c 79431 | ||