Cyclic nucleotide phosphodiesterase activities in rat erythrocytes
Erythrocyte soluble phosphodiesterase activities show at least two interconvertible states: 'aggregated' and 'non-aggregated'. In the former state the existence of a high affinity component for cyclic AMP is favoured and the system is more active with cyclic AMP than with cyclic...
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Martinus Nijhoff/Dr. W. Junk Publishers
1982
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Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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LEADER | 04510caa a22006977a 4500 | ||
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001 | PAPER-18397 | ||
003 | AR-BaUEN | ||
005 | 20230518204946.0 | ||
008 | 190411s1982 xx ||||fo|||| 00| 0 eng|d | ||
024 | 7 | |2 scopus |a 2-s2.0-0019948006 | |
024 | 7 | |2 cas |a cyclic AMP, 60-92-4; cyclic GMP, 7665-99-8; cyclic nucleotide phosphodiesterase, 50812-31-2; 3',5'-Cyclic-GMP Phosphodiesterase, EC 3.1.4.35; 3',5'-Cyclic-Nucleotide Phosphodiesterase, EC 3.1.4.17; Magnesium Chloride, 7786-30-3; Magnesium, 7439-95-4 | |
040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
030 | |a MCBIB | ||
100 | 1 | |a Téllez-Iñón, M.T. | |
245 | 1 | 0 | |a Cyclic nucleotide phosphodiesterase activities in rat erythrocytes |
260 | |b Martinus Nijhoff/Dr. W. Junk Publishers |c 1982 | ||
270 | 1 | 0 | |m Téllez-Iñón, M.T.; Instituto de Investigaciones Bioquimicas 'Fundacion Campomar', Obligado 2490, Buenos Aires, 1428, Argentina |
506 | |2 openaire |e Política editorial | ||
504 | |a Wells, J.N., Hardman, J.G., (1977) Adv. Cyclic Nucl. Res., 8, pp. 119-143 | ||
504 | |a Strada, S.J., Thompson, W.J., (1978) Adv. Cyclic Nucl. Res., 9, pp. 265-283 | ||
504 | |a Pichard, A.L., Cheung, W.Y., (1976) J. Biol. Chem., 251, pp. 5726-5737 | ||
504 | |a Guan, W.R., Cheung, W.Y., (1980) Arch. Biochem. Biophys., 204, pp. 191-198 | ||
504 | |a Bylund, D.B., Téllez-Iñón, M.T., Hollenberg, M.D., (1977) Life Sci., 21, pp. 403-410 | ||
504 | |a Thompson, W.J., Appleman, M.M., (1971) Biochemistry, 10, pp. 311-316 | ||
504 | |a Londesborough, J., (1976) Anal. Biochem., 71, pp. 623-629 | ||
504 | |a Patterson, W.O., Hardman, J.G., Sutherland, E.W., (1976) Mol. Cell. Endocrinol., 5, pp. 51-56 | ||
504 | |a Segel, I.H., (1975) Enzyme Kinetics, pp. 213-214. , Wiley Interscience, New York, U.S.A | ||
504 | |a Schröder, J., Rickenberg, H.V., (1973) Biochim. Biophys. Acta, 302, pp. 50-63 | ||
504 | |a Dicou, E.L., Bracet, P., (1979) Biochim. Biophys. Acta, 578, pp. 232-242 | ||
520 | 3 | |a Erythrocyte soluble phosphodiesterase activities show at least two interconvertible states: 'aggregated' and 'non-aggregated'. In the former state the existence of a high affinity component for cyclic AMP is favoured and the system is more active with cyclic AMP than with cyclic GMP as substrate. When the system is in the 'non-aggregated state', no activity with cyclic GMP is detected. Conversion to the 'non-aggregated state' is enhanced by dilution or by addition of magnesium ions. Upon isoelectric focusing of erythrocyte soluble extracts, phosphodiesterase activities can be resolved in two peaks: one specific for cyclic AMP located at pH 4.66 and the other specific for cyclic GMP focused at pH 4.95. Evidence would indicate that aggregation affects the enzyme specific for cyclic AMP. © 1982 Martinus Nijhoff/Dr W. Junk Publishers. |l eng | |
593 | |a Instituto de Investigaciones Bioquimicas 'Fundacion Campomar', Obligado 2490, Buenos Aires, 1428, Argentina | ||
690 | 1 | 0 | |a CYCLIC AMP |
690 | 1 | 0 | |a CYCLIC GMP |
690 | 1 | 0 | |a CYCLIC NUCLEOTIDE PHOSPHODIESTERASE |
690 | 1 | 0 | |a ANIMAL EXPERIMENT |
690 | 1 | 0 | |a BLOOD AND HEMOPOIETIC SYSTEM |
690 | 1 | 0 | |a ERYTHROCYTE |
690 | 1 | 0 | |a RAT |
690 | 1 | 0 | |a 3',5'-CYCLIC-GMP PHOSPHODIESTERASE |
690 | 1 | 0 | |a 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE |
690 | 1 | 0 | |a ANIMAL |
690 | 1 | 0 | |a CHROMATOGRAPHY, GEL |
690 | 1 | 0 | |a ERYTHROCYTES |
690 | 1 | 0 | |a ISOELECTRIC FOCUSING |
690 | 1 | 0 | |a KINETICS |
690 | 1 | 0 | |a MAGNESIUM |
690 | 1 | 0 | |a MAGNESIUM CHLORIDE |
690 | 1 | 0 | |a MALE |
690 | 1 | 0 | |a RATS |
690 | 1 | 0 | |a RATS, INBRED STRAINS |
690 | 1 | 0 | |a SUPPORT, NON-U.S. GOV'T |
700 | 1 | |a Torres, H.N. | |
773 | 0 | |d Martinus Nijhoff/Dr. W. Junk Publishers, 1982 |g v. 43 |h pp. 161-166 |k n. 3 |p Mol Cell Biochem |x 03008177 |w (AR-BaUEN)CENRE-3498 |t Molecular and Cellular Biochemistry | |
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856 | 4 | 0 | |u https://doi.org/10.1007/BF00223007 |y DOI |
856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_03008177_v43_n3_p161_TellezInon |y Handle |
856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03008177_v43_n3_p161_TellezInon |y Registro en la Biblioteca Digital |
961 | |a paper_03008177_v43_n3_p161_TellezInon |b paper |c PE | ||
962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
963 | |a VARI | ||
999 | |c 79350 |