Tryptophan metabolism in experimental porphyria
Although there seems to be no qualitative difference in the excretion of certain urinary metabolites of l-tryptophan between normal and porphyric rats, quantitative determination showed that there is a decrease in the level of excretion of l-kynurenine and 3-OH-kynurenine. At the same time, tryptoph...
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| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
1967
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 03329caa a22006017a 4500 | ||
|---|---|---|---|
| 001 | PAPER-1640 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518203100.0 | ||
| 008 | 190411s1967 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0014141052 | |
| 024 | 7 | |2 cas |a kynurenine, 16055-80-4, 343-65-7; tryptophan 2,3 dioxygenase, 9014-51-1; tryptophan, 6912-86-3, 73-22-3; Kynurenine, 343-65-7; Tryptophan Oxygenase, EC 1.13.11.11; Tryptophan, 73-22-3 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a BCPCA | ||
| 100 | 1 | |a Garcia, A.F. | |
| 245 | 1 | 0 | |a Tryptophan metabolism in experimental porphyria |
| 260 | |c 1967 | ||
| 270 | 1 | 0 | |m Garcia, A.F.; Catedra de Quimica Biologica I, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 520 | 3 | |a Although there seems to be no qualitative difference in the excretion of certain urinary metabolites of l-tryptophan between normal and porphyric rats, quantitative determination showed that there is a decrease in the level of excretion of l-kynurenine and 3-OH-kynurenine. At the same time, tryptophan pyrrolase activity is diminished in porphyric animals. This is interpreted as being the result, at least in part, of a competitive inhibition between the porphyrins accumulated in the liver during the state of porphyria and the tryptophan pyrrolase heme coenzyme, for the tryptophan pyrrolase apoenzyme. © 1967. |l eng | |
| 536 | |a Detalles de la financiación: * This work was supported by a grant from the Consejo National de Investigaciones Cientificas y Tecnicas, Republica Argentina. 7 Present address: Charles F. Kettering Research Laboratory, Yellow Springs, Ohio, U.S.A. {ARS}Allyl-isopropyl-acetyl-urea. | ||
| 593 | |a Catedra de Quimica Biologica I, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a KYNURENINE |
| 690 | 1 | 0 | |a TRYPTOPHAN |
| 690 | 1 | 0 | |a TRYPTOPHAN 2,3 DIOXYGENASE |
| 690 | 1 | 0 | |a ANIMAL |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CHROMATOGRAPHY |
| 690 | 1 | 0 | |a ENZYMOLOGY |
| 690 | 1 | 0 | |a LIVER |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a METABOLISM |
| 690 | 1 | 0 | |a PORPHYRIA |
| 690 | 1 | 0 | |a RAT |
| 690 | 1 | 0 | |a URINE |
| 690 | 1 | 0 | |a ANIMAL |
| 690 | 1 | 0 | |a CHROMATOGRAPHY |
| 690 | 1 | 0 | |a KYNURENINE |
| 690 | 1 | 0 | |a LIVER |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a PORPHYRIA |
| 690 | 1 | 0 | |a RATS |
| 690 | 1 | 0 | |a TRYPTOPHAN |
| 690 | 1 | 0 | |a TRYPTOPHAN OXYGENASE |
| 700 | 1 | |a Grinstein, M. | |
| 773 | 0 | |d 1967 |g v. 16 |h pp. 1967-1969 |k n. 10 |p Biochem. Pharmacol. |x 00062952 |w (AR-BaUEN)CENRE-914 |t Biochemical Pharmacology | |
| 856 | 4 | 1 | |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014141052&doi=10.1016%2f0006-2952%2867%2990307-3&partnerID=40&md5=996b3253c93bc1b0e2a4cd7d795e583b |y Registro en Scopus |
| 856 | 4 | 0 | |u https://doi.org/10.1016/0006-2952(67)90307-3 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_00062952_v16_n10_p1967_Garcia |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00062952_v16_n10_p1967_Garcia |y Registro en la Biblioteca Digital |
| 961 | |a paper_00062952_v16_n10_p1967_Garcia |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 963 | |a VARI | ||
| 999 | |c 62593 | ||