Abordaje integral para la caracterización in vitro de la dinámica endotelial

Cardiovascular diseases constitute one of the major reasons of death with high prevalence in the western industrialized societies. Endothelial dysfunction plays a fundamental role in physiopathological mechanisms and it is considered a syndrome with systemic manifestations associated with cardiovasc...

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Autor principal: Armentano, R.L
Otros Autores: Pessana, F.M, Cymberknop, L.J, Graf, S., Furfaro, A.
Formato: Acta de conferencia Capítulo de libro
Lenguaje:Español
Publicado: 2013
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Acceso en línea:Registro en Scopus
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100 1 |a Armentano, R.L. 
245 1 0 |a Abordaje integral para la caracterización in vitro de la dinámica endotelial 
260 |c 2013 
270 1 0 |m Armentano, R.L.; Departamento de Electrónica, Facultad Regional Buenos Aires, Universidad Tecnológica Nacional, Buenos Aires, Argentina; email: armen@ieee.org 
506 |2 openaire  |e Política editorial 
504 |a Bonetti, Endothelial dysfunction: A marker of atherosclerotic risk (2003) Arterioscler Thromb Vasc Biol, 23, pp. 168-175 
504 |a Lerman, A., Intact and altered endothelium in regulation of vasomotion (1992) Circulation, 86 (SUPPL. III), pp. III12-III19 
504 |a Kamiya, A., Togawa, T., Adaptive regulation of wall shear stress to flow change in the canine carotid artery (1980) Am J Physiol, 239 (1), pp. H14-H21 
504 |a Schmidt, M.A., Howe, R.T., Senturia, S.D., Haritonidis, J.H., Design and calibration of a microfabricated floating element shear stress sensor (1988) IEEE Transactions of Electron Devices, ED-35, pp. 750-757 
504 |a Shajii, J., Ng, K.Y., Schmidt, M.A., A microfabricated floating element shear stress sensor using wafer-bonding technology (1992) J. of Microelectromechanicals Systems, pp. 89-94 
504 |a Ai, L., Yu, H., Tabake, W., Paraboschi, A., Yu, F., Kim, E.S., Li, R., Hsiai, T.K., Optimization of intravascular shear stress assessment in vivo (2009) J Biomech, 42 (10), pp. 1429-1437 
504 |a Hsiai, T.K., Cho, S.K., Wong, P.K., Ing, M., Navab, M., Reddy, S., Demer, L.L., Ho, C.M., Bio-MEMS Sensors for Real-Time Shear Stress on Endothelial Cell Dynamics (2002) Proceedings of the Second Joint EMBS/BMES, Houston, TX, USA 
504 |a Naware, M., Rege, A., Genov, R., Stanacevic, M., Cauwenberghs, G., Thakor, N., Integrated Multi-electrode fluidic nitric-oxide sensor and vlsi potentiostat array (2004) Proceedings of the 2004 International Symposium on Circuits and Systems (ISCAS'04) 
520 3 |a Cardiovascular diseases constitute one of the major reasons of death with high prevalence in the western industrialized societies. Endothelial dysfunction plays a fundamental role in physiopathological mechanisms and it is considered a syndrome with systemic manifestations associated with cardiovascular significant morbidity and mortality. The concept of endothelial dysfunction might spread up to the vessels that irrigate the vascular wall and even more, the bony marrow and the progenitor cells of endothelium. The aim of this project is the implementation of an integral system for real-time processing of pressure, flow, vascular dimension, field of velocity profile and wall shear stress simultaneously (using Doppler velocimetry, computational fluid dynamics, piezoelectric and strain gauge sensors), in order to assess endothelial function. This system will constitute the gold standard of an immediate miniaturization (using bioMems), for evaluating the endothelium capability, in accordance to the development of implantable sensors with capacity of acquisition of additional magnitudes of the whole system, as temperatures, PH and Nitric Oxide. © 2013 Springer.  |l eng 
593 |a Departamento de Electrónica, Facultad Regional Buenos Aires, Universidad Tecnológica Nacional, Buenos Aires, Argentina 
593 |a Departamento de Tecnología Electrónica, Facultad de Ingeniería, Ciencias Exactas Y Naturales, Universidad Favaloro Buenos Aires, Buenos Aires, Argentina 
690 1 0 |a BIOMEMS 
690 1 0 |a CARDIOVASCULAR DISEASE 
690 1 0 |a CFD 
690 1 0 |a DOPPLER VELOCIMETRY 
690 1 0 |a ENDOTHELIAL CELLS 
690 1 0 |a CARDIO-VASCULAR DISEASE 
690 1 0 |a DOPPLER VELOCIMETRY 
690 1 0 |a ENDOTHELIAL DYSFUNCTION 
690 1 0 |a ENDOTHELIAL FUNCTION 
690 1 0 |a IMPLANTABLE SENSORS 
690 1 0 |a REALTIME PROCESSING 
690 1 0 |a STRAIN GAUGE SENSORS 
690 1 0 |a VELOCITY PROFILES 
690 1 0 |a BIOMEDICAL ENGINEERING 
690 1 0 |a BIOMEMS 
690 1 0 |a COMPUTATIONAL FLUID DYNAMICS 
690 1 0 |a DISEASES 
690 1 0 |a DOPPLER EFFECT 
690 1 0 |a NITRIC OXIDE 
690 1 0 |a ENDOTHELIAL CELLS 
650 1 7 |2 spines  |a MICA 
700 1 |a Pessana, F.M. 
700 1 |a Cymberknop, L.J. 
700 1 |a Graf, S. 
700 1 |a Furfaro, A. 
711 2 |c Habana  |q 5th Latin American Congress on Biomedical Engineering, CLAIB 2011  |d 16 May 2011 through 21 May 2011  |g Código de la conferencia: 95880  |g Esponsor de la conferencia: SKAN AG; Materialise NV; Bavarian Minist. Econ., Aff., Infrastruct., Transp. Technol.; Bavarian Bureau for International Business Relations GmbH; AKUD - Med Pharm GmbH 
773 0 |d 2013  |g v. 33 IFMBE  |h pp. 1126-1129  |p IFMBE Proc.  |x 16800737  |z 9783642211973  |t IFMBE Proceedings 
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