Improved synthesis of phytanyl α-D-cellobiosyldiphosphate as substrate for α-D-mannosyltransferase

Polyisoprenyl-pyrophosphate-linked cellobiose is the natural acceptor of the α-1,3-mannosyltransferase AceA from Acetobacter xylinum, which transfers mannose from GDPmannose during the assembly of the heptasaccharide repeat unit of the exopolysaccharide acetan. Phytanyl α-D- cellobiosyldiphosphate 4...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autor principal: Barrios, P.
Otros Autores: Ielpi, L., Marino, C.
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: Arkat 2011
Acceso en línea:Registro en Scopus
Handle
Registro en la Biblioteca Digital
Aporte de:Registro referencial: Solicitar el recurso aquí
LEADER 04641caa a22006137a 4500
001 PAPER-10614
003 AR-BaUEN
005 20230518204040.0
008 190411s2011 xx ||||fo|||| 00| 0 eng|d
024 7 |2 scopus  |a 2-s2.0-79955434479 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
030 |a AGFUA 
100 1 |a Barrios, P. 
245 1 0 |a Improved synthesis of phytanyl α-D-cellobiosyldiphosphate as substrate for α-D-mannosyltransferase 
260 |b Arkat  |c 2011 
270 1 0 |m Barrios, P.; Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 1428 Buenos Aires, Argentina 
506 |2 openaire  |e Política editorial 
504 |a Raetz, C.R.H., Whitfield, C., (2002) Annu. Rev. Biochem., 71, p. 635 
504 |a Whitfield, C., (2006) Ann. Rev. Biochem., 75, p. 39 
504 |a Guo, H., Yi, W., Song, J.K., Wang, P.G., (2008) Curr. Top. Med. Chem., 8, p. 141 
504 |a Lairson, L.L., Henrissat, B., Davies, G.J., Withers, S.G., (2008) Annu. Rev. Biochem., 77, p. 521 
504 |a Breton, C., Šnajdrová, L., Jeanneau, C., Koca, J., Imberty, A., (2006) Glycobiology, 16, pp. 29R 
504 |a www.cazy.org; Cantarel, B.L., Coutinho, P.M., Rancurel, C., Bernard, T., Lombard, V., Henrissat, B., (2009) Nucl. Acids Res., 37, pp. D233 
504 |a Men, H., Park, P., Ge, M., Walker, S., (1998) J. Am. Chem. Soc, 120, p. 2484 
504 |a Ye, X.-Y., Lo, M.-C., Brunner, L., Walker, D., Kahne, D., Walker, S.J., (2001) Am. Chem. Soc, 123, p. 3155 
504 |a Chen, L., Men, H., Ha, S., Ye, X.Y., Brunner, L., Hu, Y., Walker, S., (2002) Biochemistry, 41, p. 6824 
504 |a Couso, R.O., Ielpi, L., Dankert, M.A., (1987) J. Gen. Microbiol., 133, p. 2123 
504 |a Couso, R.O., Ielpi, L., Dankert, M.A., (1996) J. Bacteriol., 178, p. 4814 
504 |a Abdian, P.L., Lellouch, A.C., Gautier, C., Ielpi, L., Geremia, R.A., (2000) J. Biol. Chem., 275, p. 40568 
504 |a Couso, R.O., Ielpi, L., Garcia, R.C., Dankert, M.A., (1982) Eur. J. Biochem., 123, p. 617 
504 |a Lellouch, A.C., Watt, G.M., Geremia, R.A., Flitsch, S.L., (2000) Biochem. Biophys. Res. Communn., 272, p. 290 
504 |a Kovac, J., Kovac, P.J., (1999) Carbohydr. Chem., 18, p. 461 
504 |a Sabesan, S., Neira, S., (1992) Carbohydr. Res., 223, p. 169 
504 |a Perich, J.W., Johns, R.B., (1988) Synthesis, 142 
504 |a Bax, A., Davis, D.G., (1985) J. Magn. Reson., 65, p. 355 
504 |a Bax, A., Griffey, R.H., Hawkins, B.L., (1983) J. Magn. Reson., 55, p. 301 
504 |a Braunschweiler, L., Ernst, R.R., (1983) J. Magn. Reson., 53, p. 521 
504 |a Flitsch, S.L., Pinches, H.L., Taylor, J.P., Turner, N.J., (1992) J. Chem. Soc Perkin Trans., 1, p. 2087 
520 3 |a Polyisoprenyl-pyrophosphate-linked cellobiose is the natural acceptor of the α-1,3-mannosyltransferase AceA from Acetobacter xylinum, which transfers mannose from GDPmannose during the assembly of the heptasaccharide repeat unit of the exopolysaccharide acetan. Phytanyl α-D- cellobiosyldiphosphate 4 has been previously synthesized as an analogue acceptor by condensation of hepta-O-acetyl-α-D-cellobiosylphosphate 1 with phytanylphosphate 2, but the procedure was briefly described. We report here a modified detailed synthesis of 4. The complete NMR characterization of 4 is provided and also a selection of NMR signals of all the intermediate compounds which facilitate monitoring the synthesis. © ARKAT-USA, Inc.  |l eng 
593 |a Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 1428 Buenos Aires, Argentina 
593 |a Fundación Instituto Leloir, IIBBA-CONICET, Av Patricias Argentinas 435, 1405 Buenos Aires, Argentina 
690 1 0 |a ACETOBACTER XYLINIUM 
690 1 0 |a GLYCOSYL PHOSPHATE 
690 1 0 |a MANNOSYLTRANSFERASE 
690 1 0 |a PHYTANYL PHOSPHATE 
700 1 |a Ielpi, L. 
700 1 |a Marino, C. 
773 0 |d Arkat, 2011  |g v. 2011  |h pp. 38-48  |k n. 7  |p Arkivoc  |x 1551-7012  |t Arkivoc 
856 4 1 |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-79955434479&partnerID=40&md5=6e7d3f3e23609b8007b2e72985f1b793  |y Registro en Scopus 
856 4 0 |u https://hdl.handle.net/20.500.12110/paper_1551-701_v2011_n7_p38_Barrios  |y Handle 
856 4 0 |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_1551-701_v2011_n7_p38_Barrios  |y Registro en la Biblioteca Digital 
961 |a paper_1551-701_v2011_n7_p38_Barrios  |b paper  |c PE 
962 |a info:eu-repo/semantics/article  |a info:ar-repo/semantics/artículo  |b info:eu-repo/semantics/publishedVersion 
999 |c 71567