Animals CD103 antigen CD4+ CD25+ T lymphocyte Disease Models, Animal Flow Cytometry Forkhead Transcription Factors Galectin 3 Galectin-3 IL-10 Immunohistochemistry Leishmania major Leishmaniasis, Cutaneous Mice Mice, Inbred BALB C Mice, Knockout Notch signaling Notch1 receptor Real-Time Polymerase Chain Reaction Receptors, Notch Reverse Transcriptase Polymerase Chain Reaction T regulatory (Treg) cells T-Lymphocytes, Regulatory animal experiment animal model animal tissue antigen expression article controlled study disease course disease severity