Animals CDON gene Cell Adhesion Molecules Cell Cycle Proteins Cell Line Erinaceidae GPI-Linked Proteins Gene Expression Regulation Hedgehog Proteins Holoprosencephaly Humans Mice Mutation Protein Binding Receptors, Cell Surface Repetitive Sequences, Amino Acid Tumor Suppressor Proteins animal cell article embryo gene gene expression holoprosencephaly human missense mutation mouse nonhuman nucleotide sequence priority journal protein Patched 1