1 ,3-Dipolarcycloaddition Article Azomethine ylides Bicyclic systems Bridged Bicyclo Compounds Carbonyl groups Cycloaddition Reaction Enantiomers Enzyme Inhibitors Glycoside Hydrolases Hydrolysis Ketones Models, Molecular Molecular Conformation Natural amino acids No inhibitory activities Oxidation-Reduction Penicillium Polyhydroxylated Pyrrolidines Stereoisomerism Trifluoroacetates antagonists and inhibitors azomethine ylide bridged bicyclo compounds carbonyl derivative chemical structure conformation cycloaddition drug effect