Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase

por Szajnman, S.H., García Liñares, G.E., Li, Z.-H., Jiang, C., Galizzi, M., Bontempi, E.J., Ferella, M., Moreno, S.N.J., Docampo, R., Rodriguez, J.B.

Solanesyl diphosphate synthase, an enzyme of the ubiquinone synthetic pathway, is required throughout the life cycle of Trypanosoma brucei

por Lai, D.-H., Poropat, E., Pravia, C., Landoni, M., Couto, A.S., Pérez Rojo, F.G., Fuchs, A.G., Dubin, M., Elingold, I., Rodríguez, J.B., Ferella, M., Esteva, M.I., Bontempi, E.J., Lukeš, J.