7 aminodactinomycin Atmospheric temperature Base Sequence Binding isotherms Binding sites Complex dissociation Complex formations DNA DNA sequence DNA sequences DNA structure Dactinomycin Diffusers (optical) Fluorescent Dyes Genes Initial rate Ionic strength Kinetics Nucleic Acid Conformation Nucleic acids Organic acids Secondary structures Stoichiometry Thermodynamics article binding affinity binding assay binding kinetics complex formation dissociation