male mouse nonhuman 509 controlled study 454 Animals 412 Mice 406 animal experiment 402 Male 379 article 378 priority journal 369 animal tissue 287 animal model 265 animal cell 233 animal 196 female 196 metabolism 151 Article 148 protein expression 136 Female 131 unclassified drug 114 human 103 Mice, Inbred C57BL 84 in vitro study 82 physiology 82 Humans 77 drug effect 77 enzyme activity 76 in vivo study 75 genetics 72 Mice, Inbred BALB C 68