article human signal transduction controlled study 171 Humans 164 human cell 159 priority journal 158 protein expression 94 nonhuman 91 Signal Transduction 88 metabolism 77 Animals 76 animal cell 62 unclassified drug 54 Mice 53 protein phosphorylation 53 Female 51 mouse 51 protein function 51 cell proliferation 50 female 46 Cell Line, Tumor 43 phosphatidylinositol 3 kinase 42 enzyme activation 41 enzyme activity 39 mitogen activated protein kinase 39 Cell Line 38 Phosphorylation 37 genetics 37 cell line 36