human unclassified drug Humans 603 controlled study 479 nonhuman 474 priority journal 456 article 436 human cell 414 Animals 378 metabolism 239 protein expression 231 Article 194 animal cell 188 animal 186 mouse 166 Mice 149 chemistry 147 protein function 139 in vitro study 133 female 119 Cell Line, Tumor 115 signal transduction 113 Cell Line 111 Female 109 animal experiment 109 genetics 105 cell proliferation 97 drug effects 96 Male 94 male 94