substitution reaction 66 article 58 Substitution reactions 41 synthesis 32 unclassified drug 28 priority journal 26 chemical structure 20 chemical reaction 18 controlled study 18 reaction analysis 18 structure analysis 18 drug synthesis 16 conference paper 14 nonhuman 14 Stereoisomerism 12 Derivatives 10 Synthesis (chemical) 10 Aromatic compounds 9 Magnetic Resonance Spectroscopy 8 Molecular structure 8 Nuclear magnetic resonance spectroscopy 8 Water 8 catalysis 8 chemical bond 8 complex formation 8 glucose 8 hydrolysis 8 molecular interaction 8 stereochemistry 8 toluene 8