Binding energy 4 Molecular dynamics 4 Two domains 4 A4085T 3 ADAMTS13 3 CUB-2 DOMAIN 3 D1362V MISSENSE MUTATION 3 DOMINIO CUB-2 3 MUTACION DE SENTIDO ERRONEO D1362V 3 MUTAGENESIS SITIO-DIRIGIDA 3 SITE-DIRECTED MUTAGENESIS 3 ATP binding 2 Activation loops 2 Active site 2 Adenosine Triphosphate 2 Allosteric Regulation 2 Amino acids 2 Binding properties 2 Binding studies 2 Biochemistry 2 Biophysical studies 2 Bound state 2 CO and NO 2 CO sensing 2 Carbon monoxide 2 Catalyst activity 2 Catalytic activity 2 Combined resonance 2 Conformational change 2 Correlated dynamics 2