DNA flanking region 20 article 20 controlled study 20 DNA sequence 14 metabolism 14 promoter region 14 Humans 12 gene deletion 12 genetics 12 priority journal 12 Animals 10 Promoter Regions (Genetics) 10 Sequence Analysis, DNA 10 human 10 nonhuman 10 reporter gene 10 sequence analysis 10 transcription regulation 10 Cloning, Molecular 8 RNA 8 Transcription, Genetic 8 biosynthesis 8 female 8 heme 8 nucleotide sequence 8 Amino Acid Motifs 6 Exons 6 Felis catus 6 Genes, Reporter 6 Mice 6