5 aminolevulinate synthase 152 article 134 5-Aminolevulinate Synthetase 114 nonhuman 110 Liver 74 animal experiment 72 priority journal 72 controlled study 68 Heme 60 Support, Non-U.S. Gov't 60 heme 60 porphyrin 54 Animals 50 Porphyrins 50 metabolism 50 Animal 48 enzyme activity 48 male 48 mouse 48 Male 46 animal model 46 rat 46 Mice 44 animal tissue 44 liver 44 Rats 38 biosynthesis 36 Animalia 34 heme oxygenase 30 heme synthesis 30