unclassified drug ligand binding 82 article 66 nonhuman 60 priority journal 58 Animals 46 controlled study 46 molecular dynamics 36 Ligands 32 Humans 30 Protein Binding 28 conformational transition 28 ligand 26 animal cell 24 human 22 Binding Sites 20 Molecular dynamics 20 binding site 20 glucocorticoid receptor 20 protein function 20 Models, Molecular 18 Molecular Dynamics Simulation 18 dexamethasone 18 metabolism 18 Protein Conformation 16 Rats 16 Receptors, Glucocorticoid 16 binding affinity 16 crystal structure 16 drug mechanism 16