reactive oxygen metabolite controlled study 126 Reactive Oxygen Species 120 nonhuman 120 metabolism 114 article 108 priority journal 106 Animals 98 oxidative stress 76 human 72 Article 68 Humans 66 enzyme activity 58 Oxidative Stress 56 animal 48 unclassified drug 48 Mice 44 animal experiment 44 animal cell 42 apoptosis 42 human cell 42 mouse 42 animal tissue 40 protein expression 38 rat 38 catalase 36 superoxide dismutase 36 drug effects 34 genetics 34 glutathione 34