protein p53 human 56 Humans 54 controlled study 54 priority journal 54 article 52 Tumor Suppressor Protein p53 48 nonhuman 44 protein expression 42 human cell 38 Animals 32 Cell Line, Tumor 32 metabolism 30 protein function 30 animal cell 24 apoptosis 24 mouse 24 Apoptosis 22 cell proliferation 22 unclassified drug 22 Mice 20 cell cycle 20 signal transduction 20 enzyme activity 18 gene expression 18 in vivo study 18 protein binding 18 protein localization 18 protein protein interaction 18 Article 16