priority journal unclassified drug nonhuman 480 article 424 controlled study 420 protein expression 346 Animals 344 Humans 232 animal cell 220 human 218 protein function 168 Mice 152 mouse 152 gene expression 148 metabolism 144 animal experiment 130 human cell 124 messenger RNA 122 Female 112 signal transduction 110 female 100 Article 94 animal 94 animal tissue 94 genetics 94 Signal Transduction 88 gene expression regulation 88 protein localization 84 nucleotide sequence 82 enzyme activity 80