phosphatidylinositol 3 kinase priority journal 120 controlled study 110 article 106 signal transduction 104 human 92 protein kinase B 86 nonhuman 84 human cell 74 Animals 70 Humans 70 Signal Transduction 70 protein expression 70 1-Phosphatidylinositol 3-Kinase 56 animal cell 56 apoptosis 50 metabolism 50 protein phosphorylation 50 Proto-Oncogene Proteins c-akt 48 enzyme activation 48 cell proliferation 46 female 46 Apoptosis 44 mitogen activated protein kinase 44 Female 42 Phosphorylation 42 unclassified drug 42 mouse 40 protein function 36 Cell Line, Tumor 34