nonhuman protein expression controlled study 860 Animals 822 priority journal 820 article 808 animal cell 566 animal experiment 476 mouse 462 Mice 420 unclassified drug 398 animal tissue 376 human 360 Humans 338 female 314 Female 292 male 286 animal model 282 metabolism 272 protein function 264 animal 262 Male 234 rat 218 Article 212 signal transduction 204 enzyme activity 200 messenger RNA 198 Rats 184 human cell 174 cell proliferation 164