human 78 human cell 78 metabolism physiology Humans 76 controlled study 68 article 54 priority journal 54 signal transduction 38 Animals 34 animal 34 Cell Line 28 cell culture 28 cell line 28 female 28 nonhuman 28 drug effect 26 Cells, Cultured 24 genetics 24 unclassified drug 24 Article 22 Signal Transduction 22 mouse 22 protein expression 22 Female 20 Mice 20 apoptosis 20 animal cell 18 genetic transfection 18 mitogen activated protein kinase 16