animal model male nonhuman 404 animal experiment 384 controlled study 378 Animals 304 article 302 priority journal 288 mouse 278 Male 272 animal tissue 232 Mice 220 animal cell 168 female 132 protein expression 118 rat 98 Article 94 animal 88 in vivo study 78 Female 76 human 76 unclassified drug 76 Rats 72 in vitro study 66 metabolism 66 Humans 64 enzyme activity 64 drug effect 52 human cell 50 cell proliferation 48