intensive care Adult 2 Aged 2 Antiplasmin 2 Hemostasis 2 Humans 2 Middle Aged 2 Plasminogen 2 Prognosis 2 Prospective Studies 2 Sepsis 2 adult 2 aged 2 alpha 2 antiplasmin 2 antiplasmin 2 antithrombin 2 article 2 blood clotting 2 controlled study 2 elastase alpha 1 protease inhibitor 2 elastase inhibitor 2 enzyme activity 2 fibrinolysis 2 hemostasis 2 human 2 immunoblotting 2 major clinical study 2 plasminogen 2 plasminogen activator inhibitor 2 priority journal 2