human 16 hyperhomocysteinemia Humans 14 priority journal 14 Homocysteine 12 article 12 controlled study 12 homocysteine 12 Hyperhomocysteinemia 8 risk factor 8 Aged 6 Female 6 Male 6 Middle Aged 6 adult 6 female 6 major clinical study 6 male 6 5,10 methylenetetrahydrofolate reductase (FADH2) 4 Adult 4 Aged, 80 and over 4 Article 4 Case-Control Studies 4 Folic Acid 4 N-homocysteinylation 4 Reference Values 4 aged 4 anticoagulation 4 capillary zone electrophoresis 4 disease association 4