human 144 human cell controlled study 118 Humans 110 article 110 priority journal 104 signal transduction 88 mitogen activated protein kinase 70 metabolism 64 protein expression 62 Animals 54 mitogen activated protein kinase 1 50 Signal Transduction 46 enzyme activation 46 mouse 46 unclassified drug 46 phosphatidylinositol 3 kinase 44 protein phosphorylation 44 MAP Kinase Signaling System 42 Western blotting 42 cell proliferation 42 mitogen activated protein kinase 3 42 nonhuman 42 Female 40 Mice 40 Phosphorylation 38 2 (2 amino 3 methoxyphenyl)chromone 36 leptin 36 protein kinase B 36 Article 34