enzymatic degradation nonhuman 10 unclassified drug 8 Article 6 article 6 glucose 6 in vitro study 6 priority journal 6 Acetyltransferases 4 Amikacin 4 Aminoglycoside 4 Antibiotic resistance 4 Antisense 4 Bacteria (microorganisms) 4 Base Sequence 4 DNA 4 Drug Resistance, Bacterial 4 Endocytosis 4 Escherichia coli 4 Nucleic acids analogs 4 Oligonucleotides 4 RNA, Messenger 4 RNase P 4 Ribonuclease P 4 aac(6') Ib enzyme 4 amikacin 4 antibiotic resistance 4 antisense oligonucleotide 4 bacterial DNA 4 bacterial enzyme 4