cyclic AMP signal transduction promoter region 22 article 20 priority journal 20 cyclic AMP dependent protein kinase 18 Cyclic AMP 14 cell line 14 controlled study 14 mitogen activated protein kinase 14 protein expression 14 protein phosphorylation 14 Animals 12 Signal Transduction 12 animal cell 12 cyclic AMP responsive element binding protein 12 enzyme activation 12 enzyme inhibition 12 explant 12 human 12 human cell 12 leptin 12 mitogen activated protein kinase 1 12 nonhuman 12 plasmid 12 Mice 10 animal 10 genetics 10 metabolism 10 mouse 10