controlled study signal transduction priority journal 432 article 420 nonhuman 398 Animals 330 human 272 animal cell 268 Humans 232 metabolism 222 Signal Transduction 218 mouse 218 human cell 206 protein expression 202 Mice 188 female 168 animal experiment 166 unclassified drug 156 animal tissue 154 Female 152 animal 148 Article 142 cell proliferation 124 enzyme activity 122 male 116 enzyme activation 112 genetics 110 animal model 104 protein phosphorylation 102 Male 94