controlled study priority journal nonhuman 610 article 528 Animals 434 genetics 312 metabolism 296 animal cell 288 Humans 284 human 282 unclassified drug 246 mouse 234 Mice 224 protein expression 224 animal 216 Article 212 female 202 animal experiment 194 gene expression 172 male 172 human cell 168 Female 162 animal tissue 154 Male 148 signal transduction 146 animal model 126 messenger RNA 122 RNA, Messenger 120 protein function 120 gene expression regulation 112