controlled study priority journal signal transduction nonhuman 338 article 332 Animals 276 animal cell 236 human 178 mouse 178 Signal Transduction 164 protein expression 158 Mice 156 Humans 152 human cell 144 metabolism 144 animal experiment 134 animal tissue 132 female 130 Female 122 unclassified drug 110 animal 108 Article 96 cell proliferation 94 enzyme activity 90 enzyme activation 88 male 84 rat 80 animal model 78 protein phosphorylation 76 Rats 72