Article chemistry metabolism nonhuman 142 controlled study 118 unclassified drug 110 priority journal 98 Animals 82 animal 82 human 76 Humans 74 genetics 58 drug effects 44 molecular dynamics 44 enzymology 42 enzyme activity 38 animal cell 36 protein conformation 36 human cell 34 protein binding 34 amino acid sequence 32 in vitro study 30 Amino Acid Sequence 28 Molecular Dynamics Simulation 28 binding site 28 female 28 molecular model 28 mouse 28 protein domain 28 protein expression 28