article nonhuman priority journal 76 Protein Conformation 60 unclassified drug 52 protein conformation 50 controlled study 48 Animals 30 Models, Molecular 30 Humans 28 protein function 28 Protein Binding 26 conformational transition 24 molecular dynamics 24 Kinetics 22 protein structure 22 Binding Sites 20 Molecular dynamics 20 Protein Structure, Secondary 20 protein analysis 20 Proteins 18 Rats 18 protein domain 18 binding affinity 16 circular dichroism 16 protein stability 16 rat 16 Conformations 14 animal tissue 14 ligand 14