animal tissue metabolism nonhuman 324 Animals 312 animal 308 controlled study 296 animal experiment 222 priority journal 212 Article 196 mouse 164 male 148 physiology 146 female 136 Mice 132 animal cell 132 article 126 Male 114 unclassified drug 108 Female 106 genetics 98 animal model 92 drug effects 90 protein expression 84 immunohistochemistry 68 drug effect 66 messenger RNA 66 enzyme activity 64 pathology 62 rat 60 gene expression 58