3 [(3 cholamidopropyl)dimethylammonio] 1 propanesulfonic acid 2 Alzheimer disease 2 Aβ40 2 Aβ42(43) 2 PS1/βAPP complex 2 Presenilin-1 2 amino terminal sequence 2 amyloid beta protein article 2 carboxy terminal sequence 2 cell line 2 cell lysate 2 enzyme inhibitor 2 gamma secretase 2 mutant protein 2 pH 2 pathogenesis 2 precipitation 2 presenilin 1 2 priority journal 2 protein analysis 2 protein degradation 2 protein isolation 2 protein precursor 2 reaction analysis 2 βAPP 2 γ-secretase 2